KEGG   NETWORK: N01299
Entry
N01299                      Network                                

Name
Salmonella PipB2 to microtubule plus-end directed transport
Definition
PipB2 -> (KIF5+KLC) -- (TUBA+TUBB)
  Expanded
K15352 -> ((3798,3799,3800)+(3831,64837,147700,89953)) -- ((7846,10376,84790,7278,113457,112714,7277,51807)+(203068,81027,7280,347733,10381,10382,10383,84617,347688))
Class
nt06125 Membrane trafficking (bacteria)
Type
Pathogen
Pathway
hsa05132  Salmonella infection
Disease
H00113  Salmonellosis
Gene
3798  KIF5A; kinesin family member 5A
3799  KIF5B; kinesin family member 5B
3800  KIF5C; kinesin family member 5C
3831  KLC1; kinesin light chain 1
64837  KLC2; kinesin light chain 2
147700  KLC3; kinesin light chain 3
89953  KLC4; kinesin light chain 4
7846  TUBA1A; tubulin alpha 1a
10376  TUBA1B; tubulin alpha 1b
84790  TUBA1C; tubulin alpha 1c
7278  TUBA3C; tubulin alpha 3c
113457  TUBA3D; tubulin alpha 3d
112714  TUBA3E; tubulin alpha 3e
7277  TUBA4A; tubulin alpha 4a
51807  TUBA8; tubulin alpha 8
203068  TUBB; tubulin beta class I
81027  TUBB1; tubulin beta 1 class VI
7280  TUBB2A; tubulin beta 2A class IIa
347733  TUBB2B; tubulin beta 2B class IIb
10381  TUBB3; tubulin beta 3 class III
10382  TUBB4A; tubulin beta 4A class IVa
10383  TUBB4B; tubulin beta 4B class IVb
84617  TUBB6; tubulin beta 6 class V
347688  TUBB8; tubulin beta 8 class VIII
Perturbant
K15352 (PipB2)  pipB2; secreted effector protein PipB2
Reference
  Authors
Dumont A, Boucrot E, Drevensek S, Daire V, Gorvel JP, Pous C, Holden DW, Meresse S
  Title
SKIP, the host target of the Salmonella virulence factor SifA, promotes kinesin-1-dependent vacuolar membrane exchanges.
  Journal
Traffic 11:899-911 (2010)
DOI:10.1111/j.1600-0854.2010.01069.x
Reference
  Authors
Alberdi L, Vergnes A, Manneville JB, Tembo DL, Fang Z, Zhao Y, Schroeder N, Dumont A, Lagier M, Bassereau P, Redondo-Morata L, Gorvel JP, Meresse S
  Title
Regulation of kinesin-1 activity by the Salmonella enterica effectors PipB2 and SifA.
  Journal
J Cell Sci 133:jcs239863 (2020)
DOI:10.1242/jcs.239863
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