 | | NETWORK: N01322 | |
| Entry |
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| Name |
SARS-CoV-2 nsp6/13 and ORF7a/7b to IFN signaling pathway
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| Definition |
(nsp6,nsp13,ORF7a,ORF7b) -| STAT2 |
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| Expanded |
(K25016,K25022,K24581,K24582) -| 6773 |
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| Class |
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| Type |
Pathogen
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| Pathway |
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| Disease |
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| Gene |
| 6773 | STAT2; signal transducer and activator of transcription 2 |
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| Perturbant |
| K25016 (nsp6) | nsp6; SARS coronavirus non-structural protein 6 |
| K25022 (nsp13) | nsp13; SARS coronavirus helicase |
| K24581 (ORF7a) | 7a; SARS coronavirus accessory protein 7a |
| K24582 (ORF7b) | 7b; SARS coronavirus accessory protein 7b |
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| Reference |
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| Authors |
Xia H, Cao Z, Xie X, Zhang X, Chen JY, Wang H, Menachery VD, Rajsbaum R, Shi PY |
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| Title |
Evasion of Type I Interferon by SARS-CoV-2. |
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| Journal |
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| Reference |
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| Authors |
Yuen CK, Lam JY, Wong WM, Mak LF, Wang X, Chu H, Cai JP, Jin DY, To KK, Chan JF, Yuen KY, Kok KH |
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| Title |
SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists. |
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| Journal |
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| LinkDB |
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