KEGG   NETWORK: N01340
Entry
N01340                      Network                                
Name
ACH-CHRN-JAK-STAT signaling pathway
Definition
ACh -> CHRNA7 -> JAK2 -> STAT3
  Expanded
C01996 -> 1139 -> 3717 -> 6774
Class
nt06219 JAK-STAT signaling (cancer)
Type
Reference
Gene
1139  CHRNA7; cholinergic receptor nicotinic alpha 7 subunit
3717  JAK2; Janus kinase 2
6774  STAT3; signal transducer and activator of transcription 3
Metabolite
C01996  Acetylcholine
Reference
PMID:17012261
  Authors
Arredondo J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA
  Title
Receptor-mediated tobacco toxicity: cooperation of the Ras/Raf-1/MEK1/ERK and JAK-2/STAT-3 pathways downstream of alpha7 nicotinic receptor in oral keratinocytes.
  Journal
FASEB J 20:2093-101 (2006)
DOI:10.1096/fj.06-6191com
LinkDB

DBGET integrated database retrieval system