KEGG   NETWORK: N01384
Entry
N01384                      Network                                
Name
EO to DNA adducts
Definition
EO == DNA
  Expanded
C06548 == C00039
Class
nt06250 DNA adduct formation (cancer)
Type
Env factor
Pathway
hsa05204  Chemical carcinogenesis - DNA adducts
Disease
H00003  Acute myeloid leukemia
H00004  Chronic myeloid leukemia
H02418  Non-Hodgkin lymphoma
H00018  Gastric cancer
Perturbant
C06548 (EO)  Ethylene oxide
Metabolite
C00039  DNA
Reference
  Authors
Swenberg JA, Lu K, Moeller BC, Gao L, Upton PB, Nakamura J, Starr TB
  Title
Endogenous versus exogenous DNA adducts: their role in carcinogenesis, epidemiology, and risk assessment.
  Journal
Toxicol Sci 120 Suppl 1:S130-45 (2011)
DOI:10.1093/toxsci/kfq371
Reference
  Authors
Luch A.
  Title
Nature and nurture - lessons from chemical carcinogenesis.
  Journal
Nat Rev Cancer 5:113-25 (2005)
DOI:10.1038/nrc1546
Reference
PMID:7859343
  Authors
Melnick RL, Kohn MC
  Title
Mechanistic data indicate that 1,3-butadiene is a human carcinogen.
  Journal
Carcinogenesis 16:157-63 (1995)
DOI:10.1093/carcin/16.2.157
Reference
  Authors
Vincent MJ, Kozal JS, Thompson WJ, Maier A, Dotson GS, Best EA, Mundt KA
  Title
Ethylene Oxide: Cancer Evidence Integration and Dose-Response Implications.
  Journal
Dose Response 17:1559325819888317 (2019)
DOI:10.1177/1559325819888317
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