| Entry |
|
|---|
| Name |
Intrinsic pathway of coagulation cascade, F8 activation
|
|---|
| Definition |
(F8+VWF) -- (F10a,F2a) -> F8a -> (F9a+F8a) |
|---|
| Expanded |
(2157+7450) -- (C01065,C00752) -> C04001 -> (C03259+C04001) |
|---|
| Class |
|
|---|
| Type |
Reference
|
|---|
| Pathway |
| hsa04610 | Complement and coagulation cascades |
|
|---|
| Gene |
| 2157 | F8; coagulation factor VIII |
| 7450 | VWF; von Willebrand factor |
|
|---|
| Metabolite |
| C04001 | Coagulation factor VIIIa |
|
|---|
| Reference |
|
|---|
| Authors |
Samuelson Bannow B, Recht M, Negrier C, Hermans C, Berntorp E, Eichler H, Mancuso ME, Klamroth R, O'Hara J, Santagostino E, Matsushita T, Kessler C |
|---|
| Title |
Factor VIII: Long-established role in haemophilia A and emerging evidence beyond haemostasis. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Palta S, Saroa R, Palta A |
|---|
| Title |
Overview of the coagulation system. |
|---|
| Journal |
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|---|
| LinkDB |
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