KEGG   NETWORK: N01572
Entry
N01572                      Network                                
Name
RNASEH2-mediated RNA degradation in RNA-DNA hybrids
Definition
RNASEH2 -| DNA
  Expanded
(10535+79621+84153) -| C00039
Class
nt06520 CGAS-STING signaling
Type
Reference
Gene
10535  RNASEH2A; ribonuclease H2 subunit A
79621  RNASEH2B; ribonuclease H2 subunit B
84153  RNASEH2C; ribonuclease H2 subunit C
Metabolite
C00039  DNA
Reference
  Authors
Santa P, Garreau A, Serpas L, Ferriere A, Blanco P, Soni C, Sisirak V
  Title
The Role of Nucleases and Nucleic Acid Editing Enzymes in the Regulation of Self-Nucleic Acid Sensing.
  Journal
Front Immunol 12:629922 (2021)
DOI:10.3389/fimmu.2021.629922
Reference
  Authors
Crow YJ, Manel N
  Title
Aicardi-Goutieres syndrome and the type I interferonopathies.
  Journal
Nat Rev Immunol 15:429-40 (2015)
DOI:10.1038/nri3850
Reference
  Authors
Wan D, Jiang W, Hao J
  Title
Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory Response.
  Journal
Front Immunol 11:615 (2020)
DOI:10.3389/fimmu.2020.00615
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