 | | NETWORK: N10001 | |
| Entry |
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| Name |
First-generation tyrosine kinase inhibitor to BCR-ABL fusion
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| Definition |
Imatinib -| BCR-ABL1 |
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| Expanded |
D01441 -| 25v1 |
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| Type |
Drug target
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| Gene |
| 25 | ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase |
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| Variant |
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| Perturbant |
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| Reference |
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| Authors |
Druker BJ, Tamura S, Buchdunger E, Ohno S, Segal GM, Fanning S, Zimmermann J, Lydon NB |
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| Title |
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. |
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| Journal |
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| Reference |
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| Authors |
Carroll M, Ohno-Jones S, Tamura S, Buchdunger E, Zimmermann J, Lydon NB, Gilliland DG, Druker BJ |
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| Title |
CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins. |
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| Journal |
Blood 90:4947-52 (1997) |
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| LinkDB |
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