Entry |
|
Name |
First-generation tyrosine kinase inhibitor to ALK fusion
|
Definition |
Crizotinib -| (EML4-ALK,CD74/SLC34A2-ROS1) |
Expanded |
D09731 -| (238v1,6098v1) |
Type |
Drug target
|
Gene |
238 | ALK; ALK receptor tyrosine kinase |
6098 | ROS1; ROS proto-oncogene 1, receptor tyrosine kinase |
|
Variant |
|
Perturbant |
|
Reference |
|
Authors |
Mano H |
Title |
The EML4-ALK oncogene: targeting an essential growth driver in human cancer. |
Journal |
|
Reference |
|
Authors |
Rothschild SI, Gautschi O |
Title |
Crizotinib in the treatment of non--small-cell lung cancer. |
Journal |
|
LinkDB |
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