KEGG   REACTION: R00256
Entry
R00256                      Reaction                               
Name
L-glutamine amidohydrolase
Definition
L-Glutamine + H2O <=> L-Glutamate + Ammonia
Equation
C00064 + C00001 <=> C00025 + C00014
Comment
ec 2.6.1.85 (see R01716, R00256+R05552)
ec 6.3.4.2 (see R00573, R00256+R00571)
ec 6.3.5.4 (see R00578, R00256+R00483)
ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)
ec 2.6.1.123 (see R12939, R00256+R12937+R12938)
Reaction class
RC00010  C00025_C00064
RC02798  C00014_C00064
Enzyme
1.4.1.13        1.4.1.14        1.4.7.1         2.6.1.85        
2.6.1.123       3.5.1.2         3.5.1.38        4.3.2.10        
4.3.3.6         6.3.4.2         6.3.5.2         6.3.5.4         
6.3.5.5         6.3.5.13
Pathway
rn00220  Arginine biosynthesis
rn00250  Alanine, aspartate and glutamate metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.4  Acting on the CH-NH2 group of donors
   1.4.1  With NAD+ or NADP+ as acceptor
    1.4.1.13
     R00256  L-Glutamine + H2O <=> L-Glutamate + Ammonia
    1.4.1.14
     R00256  L-Glutamine + H2O <=> L-Glutamate + Ammonia
   1.4.7  With an iron-sulfur protein as acceptor
    1.4.7.1
     R00256  L-Glutamine + H2O <=> L-Glutamate + Ammonia
 2. Transferase reactions
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.85
     R00256  L-Glutamine + H2O <=> L-Glutamate + Ammonia
    2.6.1.123
     R00256  L-Glutamine + H2O <=> L-Glutamate + Ammonia
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.2
     R00256  L-Glutamine + H2O <=> L-Glutamate + Ammonia
    3.5.1.38
     R00256  L-Glutamine + H2O <=> L-Glutamate + Ammonia
 4. Lyase reactions
  4.3  Carbon-nitrogen lyases
   4.3.2  Amidine-lyases
    4.3.2.10
     R00256  L-Glutamine + H2O <=> L-Glutamate + Ammonia
   4.3.3  Amine-lyases
    4.3.3.6
     R00256  L-Glutamine + H2O <=> L-Glutamate + Ammonia
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.2
     R00256  L-Glutamine + H2O <=> L-Glutamate + Ammonia
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.2
     R00256  L-Glutamine + H2O <=> L-Glutamate + Ammonia
    6.3.5.4
     R00256  L-Glutamine + H2O <=> L-Glutamate + Ammonia
    6.3.5.5
     R00256  L-Glutamine + H2O <=> L-Glutamate + Ammonia
    6.3.5.13
     R00256  L-Glutamine + H2O <=> L-Glutamate + Ammonia
Orthology
K01425  glutaminase [EC:3.5.1.2]
K01954  carbamoyl-phosphate synthase [EC:6.3.5.5]
K01955  carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
K01956  carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
K05597  glutamin-(asparagin-)ase [EC:3.5.1.38]
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
K11541  carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2]
K23265  phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
Other DBs
RHEA: 15892
LinkDB

KEGG   REACTION: R12330
Entry
R12330                      Reaction                               
Name
ATP:beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphospho-ditrans,octacis-undecaprenol phosphotransferase
Definition
ATP + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine <=> ADP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-diphospho-ditrans,octacis-undecaprenol
Equation
C00002 + C05893 <=> C00008 + C22083
Comment
a part of multi-step reaction (see R05030, R00256+R12330+R12331)
Reaction class
RC00043  C05893_C22083
Enzyme
6.3.5.13
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.13
     R12330  ATP + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine <=> ADP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-diphospho-ditrans,octacis-undecaprenol
LinkDB

KEGG   REACTION: R12331
Entry
R12331                      Reaction                               
Definition
beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-diphospho-ditrans,octacis-undecaprenol + Ammonia <=> Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine + Orthophosphate
Equation
C22083 + C00014 <=> C05894 + C00009
Comment
a part of multi-step reaction (see R05030, R00256+R12330+R12331)
Enzyme
6.3.5.13
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.13
     R12331  beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-diphospho-ditrans,octacis-undecaprenol + Ammonia <=> Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine + Orthophosphate
LinkDB

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