KEGG   REACTION: R00257
Entry
R00257                      Reaction                               
Name
deamido-NAD+:L-glutamine amido-ligase (AMP-forming)
Definition
ATP + Deamino-NAD+ + L-Glutamine + H2O <=> AMP + Diphosphate + NAD+ + L-Glutamate
Equation
C00002 + C00857 + C00064 + C00001 <=> C00020 + C00013 + C00003 + C00025
Reaction class
RC00010  C00025_C00064
RC00100  C00003_C00857
Enzyme
6.3.5.1
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00115  NAD biosynthesis, aspartate => quinolinate => NAD
M00912  NAD biosynthesis, tryptophan => quinolinate => NAD
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.1
     R00257  ATP + Deamino-NAD+ + L-Glutamine + H2O <=> AMP + Diphosphate + NAD+ + L-Glutamate
Orthology
K01950  NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]
Other DBs
RHEA: 24387
LinkDB

KEGG   RCLASS: RC00100
Entry
RC00100                     RClass                                 
Definition
C5a-C6a:N1a+*-*+O6a:C8y+O5a-C8y+O6a
Reactant pair
C00003_C00857    C00153_C00253    C00180_C09815
C00455_C01185    C03925_C16246
Related class
Reaction
R00189 R00257 R01268 R02322 R05590 R07782
Enzyme
3.5.1.4         3.5.1.19        3.5.1.42        3.5.1.-         
6.3.1.5         6.3.5.1
Pathway
rn00364  Fluorobenzoate degradation
rn00627  Aminobenzoate degradation
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Orthology
K01426  amidase [EC:3.5.1.4]
K01440  nicotinamidase [EC:3.5.1.19]
K01916  NAD+ synthase [EC:6.3.1.5]
K01950  NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]
K03742  nicotinamide-nucleotide amidase [EC:3.5.1.42]
K03743  nicotinamide-nucleotide amidase [EC:3.5.1.42]
K08281  nicotinamidase/pyrazinamidase [EC:3.5.1.19 3.5.1.-]

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