REACTION: R00268
Help
Entry
R00268 Reaction
Name
oxalosuccinate carboxy-lyase (2-oxoglutarate-forming)
Definition
Oxalosuccinate <=> 2-Oxoglutarate + CO2
Equation
C05379
<=>
C00026
+
C00011
Comment
the second step of two-step reaction (see
R00267, R01899+R00268
)
following after
R01899
Reaction class
RC00626
C00026_C05379
Enzyme
1.1.1.42
Pathway
rn00020
Citrate cycle (TCA cycle)
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
rn01120
Microbial metabolism in diverse environments
rn01210
2-Oxocarboxylic acid metabolism
Module
M00009
Citrate cycle (TCA cycle, Krebs cycle)
M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
M00740
Methylaspartate cycle
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42
R00268 Oxalosuccinate <=> 2-Oxoglutarate + CO2
BRITE hierarchy
Orthology
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Other DBs
RHEA:
19384
LinkDB
All DBs
RCLASS: RC00626
Help
Entry
RC00626 RClass
Definition
C1b-C1c:*-C6a:C1b+C5a-C1b+C5a
Reactant pair
C00026_C05379
C00136_C18026
C00322_C05533
Related class
DB search
Reaction
R00268
R01936
R08201
R08924
R09958
Enzyme
1.1.1.42
1.1.1.87
1.1.1.286
4.1.1.94
6.4.1.3
6.4.1.7
Pathway
rn00020
Citrate cycle (TCA cycle)
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
rn01120
Microbial metabolism in diverse environments
rn01210
2-Oxocarboxylic acid metabolism
RModule
RM001
2-Oxocarboxylic acid chain extension by tricarboxylic acid pathway
Orthology
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
K05824
homoisocitrate dehydrogenase [EC:
1.1.1.87
]
K10978
methanogen homoisocitrate dehydrogenase [EC:
1.1.1.87
1.1.1.-]
K17753
isocitrate--homoisocitrate dehydrogenase [EC:
1.1.1.286
]
DBGET
integrated database retrieval system