KEGG   REACTION: R00268
Entry
R00268                      Reaction                               
Name
oxalosuccinate carboxy-lyase (2-oxoglutarate-forming)
Definition
Oxalosuccinate <=> 2-Oxoglutarate + CO2
Equation
C05379 <=> C00026 + C00011
Comment
the second step of two-step reaction (see R00267, R01899+R00268)
following after R01899
Reaction class
RC00626  C00026_C05379
Enzyme
1.1.1.42
Pathway
rn00020  Citrate cycle (TCA cycle)
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
M00740  Methylaspartate cycle
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.42
     R00268  Oxalosuccinate <=> 2-Oxoglutarate + CO2
Orthology
K00031  isocitrate dehydrogenase [EC:1.1.1.42]
Other DBs
RHEA: 19384
LinkDB

KEGG   RCLASS: RC00626
Entry
RC00626                     RClass                                 
Definition
C1b-C1c:*-C6a:C1b+C5a-C1b+C5a
Reactant pair
C00026_C05379    C00136_C18026    C00322_C05533
C20876_C22857
Related class
Reaction
R00268 R01936 R08201 R08924 R09958 R13256
Enzyme
1.1.1.42        1.1.1.87        1.1.1.286       4.1.1.94        
6.4.1.3         6.4.1.7         6.4.1.-
Pathway
rn00020  Citrate cycle (TCA cycle)
rn00074  Mycolic acid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
RModule
RM001  2-Oxocarboxylic acid chain extension by tricarboxylic acid pathway
Orthology
K00031  isocitrate dehydrogenase [EC:1.1.1.42]
K05824  homoisocitrate dehydrogenase [EC:1.1.1.87]
K10978  methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]
K11263  acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
K17753  isocitrate--homoisocitrate dehydrogenase [EC:1.1.1.286]
K27093  long-chain acyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.- 2.1.3.-]
K27094  propionyl-CoA/long-chain acyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.3 6.4.1.- 2.1.3.15]
K27095  acyl-CoA carboxylase epsilon subunit

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