KEGG   REACTION: R00268
Entry
R00268                      Reaction                               
Name
oxalosuccinate carboxy-lyase (2-oxoglutarate-forming)
Definition
Oxalosuccinate <=> 2-Oxoglutarate + CO2
Equation
C05379 <=> C00026 + C00011
Comment
the second step of two-step reaction (see R00267, R01899+R00268)
following after R01899
Reaction class
RC00626  C00026_C05379
Enzyme
1.1.1.42
Pathway
rn00020  Citrate cycle (TCA cycle)
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
M00740  Methylaspartate cycle
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.42
     R00268  Oxalosuccinate <=> 2-Oxoglutarate + CO2
Orthology
K00031  isocitrate dehydrogenase [EC:1.1.1.42]
Other DBs
RHEA: 19384
LinkDB

KEGG   RCLASS: RC00626
Entry
RC00626                     RClass                                 
Definition
C1b-C1c:*-C6a:C1b+C5a-C1b+C5a
Reactant pair
C00026_C05379    C00136_C18026    C00322_C05533
Related class
Reaction
R00268 R01936 R08201 R08924 R09958
Enzyme
1.1.1.42        1.1.1.87        1.1.1.286       4.1.1.94        
6.4.1.3         6.4.1.7
Pathway
rn00020  Citrate cycle (TCA cycle)
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
RModule
RM001  2-Oxocarboxylic acid chain extension by tricarboxylic acid pathway
Orthology
K00031  isocitrate dehydrogenase [EC:1.1.1.42]
K05824  homoisocitrate dehydrogenase [EC:1.1.1.87]
K10978  methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]
K17753  isocitrate--homoisocitrate dehydrogenase [EC:1.1.1.286]

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