REACTION: R00268
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Entry
R00268 Reaction
Name
oxalosuccinate carboxy-lyase (2-oxoglutarate-forming)
Definition
Oxalosuccinate <=> 2-Oxoglutarate + CO2
Equation
C05379
<=>
C00026
+
C00011
Comment
the second step of two-step reaction (see
R00267, R01899+R00268
)
following after
R01899
Reaction class
RC00626
C00026_C05379
Enzyme
1.1.1.42
Pathway
rn00020
Citrate cycle (TCA cycle)
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
rn01120
Microbial metabolism in diverse environments
rn01210
2-Oxocarboxylic acid metabolism
Module
M00009
Citrate cycle (TCA cycle, Krebs cycle)
M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
M00740
Methylaspartate cycle
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42
R00268 Oxalosuccinate <=> 2-Oxoglutarate + CO2
BRITE hierarchy
Orthology
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Other DBs
RHEA:
19384
LinkDB
All DBs
RCLASS: RC00626
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Entry
RC00626 RClass
Definition
C1b-C1c:*-C6a:C1b+C5a-C1b+C5a
Reactant pair
C00026_C05379
C00136_C18026
C00322_C05533
C20876_C22857
Related class
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Reaction
R00268
R01936
R08201
R08924
R09958
R13256
Enzyme
1.1.1.42
1.1.1.87
1.1.1.286
4.1.1.94
6.4.1.3
6.4.1.7
6.4.1.-
Pathway
rn00020
Citrate cycle (TCA cycle)
rn00074
Mycolic acid biosynthesis
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
rn01120
Microbial metabolism in diverse environments
rn01210
2-Oxocarboxylic acid metabolism
RModule
RM001
2-Oxocarboxylic acid chain extension by tricarboxylic acid pathway
Orthology
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
K05824
homoisocitrate dehydrogenase [EC:
1.1.1.87
]
K10978
methanogen homoisocitrate dehydrogenase [EC:
1.1.1.87
1.1.1.-]
K11263
acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:
6.4.1.2
6.4.1.3
6.4.1.-
6.3.4.14
]
K17753
isocitrate--homoisocitrate dehydrogenase [EC:
1.1.1.286
]
K27093
long-chain acyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.- 2.1.3.-]
K27094
propionyl-CoA/long-chain acyl-CoA carboxylase carboxyl transferase subunit [EC:
6.4.1.3
6.4.1.-
2.1.3.15
]
K27095
acyl-CoA carboxylase epsilon subunit
DBGET
integrated database retrieval system