KEGG   REACTION: R00552
Entry
R00552                      Reaction                               
Name
L-arginine iminohydrolase
Definition
L-Arginine + H2O <=> L-Citrulline + Ammonia
Equation
Reaction class
RC00177  C00062_C00327
Enzyme
Pathway
rn00220  Arginine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.3  In linear amidines
    3.5.3.6
     R00552  L-Arginine + H2O <=> L-Citrulline + Ammonia
Orthology
K01478  arginine deiminase [EC:3.5.3.6]
Other DBs
RHEA: 19600
LinkDB

KEGG   REACTION: R00557
Entry
R00557                      Reaction                               
Name
L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming)
Definition
2 L-Arginine + 4 Oxygen + 3 NADPH + 3 H+ <=> 2 Nitric oxide + 2 L-Citrulline + 3 NADP+ + 4 H2O
Equation
2 C00062 + 4 C00007 + 3 C00005 + 3 C00080 <=> 2 C00533 + 2 C00327 + 3 C00006 + 4 C00001
Comment
multi-step reaction (see R00558+R00111)
NADH (see R10106)
Reaction class
RC00001  C00005_C00006
RC00177  C00062_C00327
Enzyme
Pathway
rn00220  Arginine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.39
     R00557  2 L-Arginine + 4 Oxygen + 3 NADPH + 3 H+ <=> 2 Nitric oxide + 2 L-Citrulline + 3 NADP+ + 4 H2O
Orthology
K13240  nitric-oxide synthase, brain [EC:1.14.13.39]
K13241  nitric-oxide synthase, inducible [EC:1.14.13.39]
K13242  nitric-oxide synthase, endothelial [EC:1.14.13.39]
K13427  nitric-oxide synthase, plant [EC:1.14.13.39]
Other DBs
RHEA: 19900
LinkDB

KEGG   RCLASS: RC00177
Entry
RC00177                     RClass                                 
Definition
C2c-C5a:N2a+*-*+O5a:N1a+N1b-N1a+N1b
Reactant pair
Related class
Reaction
Enzyme
1.14.13.39      1.14.14.47      3.5.3.6         3.5.3.12        
3.5.3.15
Pathway
rn00220  Arginine biosynthesis
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K00491  nitric-oxide synthase, bacterial [EC:1.14.14.47]
K01478  arginine deiminase [EC:3.5.3.6]
K10536  agmatine deiminase [EC:3.5.3.12]
K13240  nitric-oxide synthase, brain [EC:1.14.13.39]
K13241  nitric-oxide synthase, inducible [EC:1.14.13.39]
K13242  nitric-oxide synthase, endothelial [EC:1.14.13.39]
K13427  nitric-oxide synthase, plant [EC:1.14.13.39]

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