KEGG   REACTION: R00575
Entry
R00575                      Reaction                               
Name
HCO3-:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating)
Definition
2 ATP + L-Glutamine + HCO3- + H2O <=> 2 ADP + Orthophosphate + L-Glutamate + Carbamoyl phosphate
Equation
2 C00002 + C00064 + C00288 + C00001 <=> 2 C00008 + C00009 + C00025 + C00169
Comment
multi-step reaction (see R00256+R10948+R10949+R01395)
Reaction class
RC00002  C00002_C00008
RC00010  C00025_C00064
RC02750  C00064_C00169
Enzyme
6.3.5.5
Pathway
rn00240  Pyrimidine metabolism
rn00250  Alanine, aspartate and glutamate metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Orthology
K01954  carbamoyl-phosphate synthase [EC:6.3.5.5]
K01955  carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
K01956  carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
K11541  carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2]
Other DBs
RHEA: 18636
LinkDB

KEGG   RCLASS: RC02750
Entry
RC02750                     RClass                                 
Definition
N1a-N1a:C5a+*-*+C7a:*-*
Reactant pair
C00064_C00169
Related class
Reaction
R00575
Enzyme
6.3.5.5
Pathway
rn00240  Pyrimidine metabolism
rn00250  Alanine, aspartate and glutamate metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Orthology
K01954  carbamoyl-phosphate synthase [EC:6.3.5.5]
K01955  carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
K01956  carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
K11541  carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2]

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