KEGG   REACTION: R00702
Entry
R00702                      Reaction                               
Name
farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase
Definition
2 trans,trans-Farnesyl diphosphate <=> Diphosphate + Presqualene diphosphate
Equation
2 C00448 <=> C00013 + C03428
Comment
the first step of two-step reaction (R06223, R00702+R02872)
the first step of two-step reaction (R07652, R00702+R09793)
Reaction class
RC00362  C00448_C03428
Enzyme
2.5.1.21        2.5.1.96        2.5.1.103
Pathway
rn00100  Steroid biosynthesis
rn00906  Carotenoid biosynthesis
rn00909  Sesquiterpenoid and triterpenoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00101  Cholesterol biosynthesis, FPP => cholesterol
M00102  Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.21
     R00702  2 trans,trans-Farnesyl diphosphate <=> Diphosphate + Presqualene diphosphate
    2.5.1.96
     R00702  2 trans,trans-Farnesyl diphosphate <=> Diphosphate + Presqualene diphosphate
    2.5.1.103
     R00702  2 trans,trans-Farnesyl diphosphate <=> Diphosphate + Presqualene diphosphate
Orthology
K00801  farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
K10208  4,4'-diapophytoene synthase [EC:2.5.1.96]
Other DBs
RHEA: 22675
LinkDB

KEGG   RCLASS: RC00362
Entry
RC00362                     RClass                                 
Definition
C1y-C2b:C1y-*:C1b+C1z-C1b+C2c
C1z-C2c:C1y-*:C1a+C1b+C1y-C1a+C1b+C2b
Reactant pair
C00353_C03427    C00448_C03428
Related class
Reaction
R00702 R02065
Enzyme
2.5.1.21        2.5.1.32        2.5.1.96        2.5.1.103       
2.5.1.148
Pathway
rn00100  Steroid biosynthesis
rn00906  Carotenoid biosynthesis
rn00909  Sesquiterpenoid and triterpenoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K00801  farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
K02291  15-cis-phytoene synthase [EC:2.5.1.32]
K10208  4,4'-diapophytoene synthase [EC:2.5.1.96]
K17841  15-cis-phytoene synthase / lycopene beta-cyclase [EC:2.5.1.32 5.5.1.19]
K23152  lycopaoctaene synthase [EC:2.5.1.148]

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