REACTION: R00888
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Entry
R00888 Reaction
Name
GDP-alpha-D-mannose 4,6-hydro-lyase (GDP-4-dehydro-alpha-D-rhamnose-forming);
GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming)
Definition
GDP-mannose <=> GDP-4-dehydro-6-deoxy-D-mannose + H2O
Equation
C00096
<=>
C01222
+
C00001
Reaction class
RC00402
C00096_C01222
Enzyme
4.2.1.47
Pathway
rn00051
Fructose and mannose metabolism
rn00541
Biosynthesis of various nucleotide sugars
rn01100
Metabolic pathways
rn01250
Biosynthesis of nucleotide sugars
Brite
Enzymatic reactions [BR:
br08201
]
4. Lyase reactions
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.47
R00888 GDP-mannose <=> GDP-4-dehydro-6-deoxy-D-mannose + H2O
BRITE hierarchy
Orthology
K01711
GDPmannose 4,6-dehydratase [EC:
4.2.1.47
]
Other DBs
RHEA:
23823
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All DBs
RCLASS: RC00402
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Entry
RC00402 RClass
Definition
C1a-C1b:*-O1a:C1y-C1y
C5x-C1y:*-*:C1y+C1y+O5x-C1y+C1y+O1a
Reactant pair
C00029_C04089
C00043_C04613
C00096_C01222
C00501_C01219
C00842_C11907
C21314_C21315
Related class
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Reaction
R00293
R00888
R02426
R06513
R10266
R11430
Enzyme
4.2.1.45
4.2.1.46
4.2.1.47
4.2.1.76
4.2.1.135
Pathway
rn00051
Fructose and mannose metabolism
rn00521
Streptomycin biosynthesis
rn00523
Polyketide sugar unit biosynthesis
rn00525
Acarbose and validamycin biosynthesis
rn00541
Biosynthesis of various nucleotide sugars
rn00552
Teichoic acid biosynthesis
rn01055
Biosynthesis of vancomycin group antibiotics
rn01059
Biosynthesis of enediyne antibiotics
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
rn01250
Biosynthesis of nucleotide sugars
Orthology
K01709
CDP-glucose 4,6-dehydratase [EC:
4.2.1.45
]
K01710
dTDP-glucose 4,6-dehydratase [EC:
4.2.1.46
]
K01711
GDPmannose 4,6-dehydratase [EC:
4.2.1.47
]
K12450
UDP-glucose 4,6-dehydratase [EC:
4.2.1.76
]
K15912
UDP-N-acetylglucosamine 4,6-dehydratase [EC:
4.2.1.135
]
K21211
NDP-hexose 4,6-dehydratase
K24300
UDP-N-acetylglucosamine 4,6-dehydratase [EC:
4.2.1.135
]
K24301
UDP-N-acetylglucosamine 4,6-dehydratase [EC:
4.2.1.135
]
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