KEGG   REACTION: R00977
Entry
R00977                      Reaction                               
Name
5,6-dihydrouracil:NAD+ oxidoreductase
Definition
5,6-Dihydrouracil + NAD+ <=> Uracil + NADH + H+
Equation
C00429 + C00003 <=> C00106 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00072  C00106_C00429
Enzyme
1.3.1.1
Pathway
rn00240  Pyrimidine metabolism
rn00410  beta-Alanine metabolism
rn00770  Pantothenate and CoA biosynthesis
rn01100  Metabolic pathways
Module
M00046  Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.1
     R00977  5,6-Dihydrouracil + NAD+ <=> Uracil + NADH + H+
Orthology
K17722  dihydropyrimidine dehydrogenase (NAD+) subunit PreT [EC:1.3.1.1]
K17723  dihydropyrimidine dehydrogenase (NAD+) subunit PreA [EC:1.3.1.1]
Other DBs
RHEA: 20192
LinkDB

KEGG   RCLASS: RC00072
Entry
RC00072                     RClass                                 
Definition
C1x-C8x:*-*:C1x+C5x-C8x+C8y
C1x-C8x:*-*:C1x+N1x-C8x+N4x
Reactant pair
C00106_C00429
Related class
Reaction
R00975 R00977 R00978
Enzyme
1.3.1.1         1.3.1.2         1.3.3.7
Pathway
rn00240  Pyrimidine metabolism
rn00410  beta-Alanine metabolism
rn00770  Pantothenate and CoA biosynthesis
rn01100  Metabolic pathways
RModule
RM024  Pyrimidine degradation
Orthology
K00207  dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2]
K17722  dihydropyrimidine dehydrogenase (NAD+) subunit PreT [EC:1.3.1.1]
K17723  dihydropyrimidine dehydrogenase (NAD+) subunit PreA [EC:1.3.1.1]

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