KEGG   REACTION: R00998
Entry
R00998                      Reaction                               
Name
acetyl-CoA:2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming);
(R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acylating)
Definition
(R)-2-Ethylmalate + CoA <=> Acetyl-CoA + H2O + 2-Oxobutanoate
Equation
C02488 + C00010 <=> C00024 + C00001 + C00109
Comment
multi-step reaction
Reaction class
RC00004  C00010_C00024
RC00067  C00109_C02488
RC02754  C00024_C02488
Enzyme
2.3.3.6
Pathway
rn00620  Pyruvate metabolism
Other DBs
RHEA: 23043
LinkDB

KEGG   RCLASS: RC02754
Entry
RC02754                     RClass                                 
Definition
C1a-C1b:*-C1d:C5a-C6a
C5a-C6a:S2a+*-*+O6a:C1a+O5a-C1b+O6a
Reactant pair
C00024_C01251    C00024_C02488    C00024_C02504
C00024_C05994
Related class
Reaction
R00271 R00998 R01213 R05063
Enzyme
2.3.3.6         2.3.3.13        2.3.3.14        4.1.3.-
Pathway
rn00300  Lysine biosynthesis
rn00620  Pyruvate metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
Orthology
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
K01655  homocitrate synthase [EC:2.3.3.14]
K02594  homocitrate synthase NifV [EC:2.3.3.14]
K10977  methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]

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