REACTION: R01565
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Entry
R01565 Reaction
Name
N,N-dimethylglycine,5,6,7,8-tetrahydrofolate:electron-transferflavoprotein oxidoreductase (demethylating,5,10-methylenetetrahydrofolate-forming)
Definition
N,N-Dimethylglycine + Tetrahydrofolate + Electron-transferring flavoprotein <=> Sarcosine + 5,10-Methylenetetrahydrofolate + Reduced electron-transferring flavoprotein
Equation
C01026
+
C00101
+
C04253
<=>
C00213
+
C00143
+
C04570
Reaction class
RC00181
C00213_C01026
Enzyme
1.5.8.4
Pathway
rn00260
Glycine, serine and threonine metabolism
rn01100
Metabolic pathways
Orthology
K00315
dimethylglycine dehydrogenase [EC:
1.5.8.4
]
Other DBs
RHEA:
52859
LinkDB
All DBs
RCLASS: RC00181
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Entry
RC00181 RClass
Definition
N1b-N1c:*-C1a:C1a+C1b-C1a+C1b
Reactant pair
C00213_C01026
C01210_C13482
C01241_C04308
C02442_C06199
C05011_C16547
C05544_C05545
C05679_C05680
C06212_C08299
C07108_C16546
C07572_C16608
C07576_C21779
C08304_C21602
C21673_C21674
Related class
DB search
Reaction
R01564
R01565
R03424
R03943
R04866
R04925
R06868
R07243
R08268
R08269
R08343
R08537
R09510
R11699
R11799
R11936
R12463
Enzyme
1.5.3.10
1.5.8.4
1.14.11.27
1.14.11.65
1.14.11.66
1.14.11.67
1.14.11.68
1.14.11.69
1.14.14.1
1.14.14.-
1.14.99.66
2.1.1.16
2.1.1.49
2.1.1.59
2.1.1.60
2.1.1.71
2.1.1.103
2.1.1.156
2.1.1.157
2.1.1.162
2.1.1.340
2.1.1.344
2.1.1.345
2.1.1.354
2.1.1.355
2.1.1.356
2.1.1.357
2.1.1.359
2.1.1.360
2.1.1.362
2.1.1.368
2.1.1.370
2.1.1.371
2.1.1.372
2.1.1.-
Pathway
rn00260
Glycine, serine and threonine metabolism
rn00310
Lysine degradation
rn00350
Tyrosine metabolism
rn00440
Phosphonate and phosphinate metabolism
rn00564
Glycerophospholipid metabolism
rn00901
Indole alkaloid biosynthesis
rn00982
Drug metabolism - cytochrome P450
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
Orthology
K00309
dimethylglycine oxidase [EC:
1.5.3.10
]
K00315
dimethylglycine dehydrogenase [EC:
1.5.8.4
]
K00550
phosphatidyl-N-methylethanolamine N-methyltransferase [EC:
2.1.1.71
]
K00551
phosphatidylethanolamine/phosphatidyl-N-methylethanolamine N-methyltransferase [EC:
2.1.1.17
2.1.1.71
]
K00570
phosphatidylethanolamine/phosphatidyl-N-methylethanolamine N-methyltransferase [EC:
2.1.1.17
2.1.1.71
]
K05929
phosphoethanolamine N-methyltransferase [EC:
2.1.1.103
]
K06101
[histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:
2.1.1.354
]
K09186
[histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:
2.1.1.354
]
K09187
[histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:
2.1.1.354
]
K09188
[histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:
2.1.1.354
]
K09189
[histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:
2.1.1.354
]
K11419
[histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:
2.1.1.355
]
K11420
[histone H3]-lysine9 N-trimethyltransferase EHMT [EC:
2.1.1.355
]
K11422
[histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:
2.1.1.354
]
K11423
[histone H3]-lysine36 N-trimethyltransferase [EC:
2.1.1.359
]
K11424
[histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:
2.1.1.357
]
K11425
[histone H3]-lysine4 N-dimethyltransferase / [histone H3]-lysine27 N-dimethyltransferase [EC:
2.1.1.370
2.1.1.371
]
K11426
[histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:
2.1.1.354
2.1.1.357
]
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
K11429
[histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:
2.1.1.362
]
K11430
[histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:
2.1.1.356
]
K11432
[histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:
2.1.1.355
]
K11433
[histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:
2.1.1.357
]
K14959
[histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:
2.1.1.354
]
K15588
[histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:
2.1.1.357
]
K17451
[histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:
2.1.1.356
]
K17689
cytochrome P450 family 3 subfamily A4 [EC:
1.14.13.32
1.14.14.55
1.14.14.56
1.14.14.57
1.14.14.73
1.14.14.-]
K17712
cytochrome P450 family 2 subfamily D6 [EC:
1.14.14.1
]
K17721
cytochrome P450 family 2 subfamily C19 [EC:
1.14.14.51
1.14.14.52
1.14.14.53
1.14.14.75
1.14.14.-]
K18494
[histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:
2.1.1.355
]
K18804
[cytochrome c]-lysine N-methyltransferase [EC:
2.1.1.59
]
K18826
calmodulin-lysine N-methyltransferase [EC:
2.1.1.60
]
K20796
[histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:
2.1.1.354
]
K21937
3-aminomethylindole N-methyltransferase [EC:
2.1.1.340
]
K22309
ornithine lipid N-methyltransferase [EC:
2.1.1.344
]
K22436
psilocybin synthase [EC:
2.1.1.345
]
K22748
[histone H3]-lysine4 N-trimethyltransferase ATXR3 [EC:
2.1.1.354
]
K23700
[histone H3]-lysine36 N-trimethyltransferase [EC:
2.1.1.359
]
K24405
[histone H3]-lysine9 N-dimethyltransferase [EC:
2.1.1.368
]
K24407
[histone H4]-lysine20 N-trimethyltransferase [EC:
2.1.1.372
]
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integrated database retrieval system
