KEGG   REACTION: R01616
Entry
R01616                      Reaction                               
Name
4-coumarate:CoA ligase (AMP-forming)
Definition
ATP + 4-Coumarate + CoA <=> AMP + Diphosphate + p-Coumaroyl-CoA
Equation
C00002 + C00811 + C00010 <=> C00020 + C00013 + C00223
Reaction class
RC00004  C00010_C00223
RC00131  C00223_C00811
Enzyme
6.2.1.12
Pathway
rn00130  Ubiquinone and other terpenoid-quinone biosynthesis
rn00940  Phenylpropanoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00039  Monolignol biosynthesis, phenylalanine/tyrosine => monolignol
M00137  Flavanone biosynthesis, phenylalanine => naringenin
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.12
     R01616  ATP + 4-Coumarate + CoA <=> AMP + Diphosphate + p-Coumaroyl-CoA
Orthology
K01904  4-coumarate--CoA ligase [EC:6.2.1.12]
Reference
1  [PMID:12232327]
  Authors
Loscher R, Heide L
  Title
Biosynthesis of p-Hydroxybenzoate from p-Coumarate and p-Coumaroyl-Coenzyme A in Cell-Free Extracts of Lithospermum erythrorhizon Cell Cultures.
  Journal
Plant Physiol 106:271-279 (1994)
DOI:10.1104/pp.106.1.271
Reference
2  [PMID:11583838]
  Authors
Meganathan R
  Title
Ubiquinone biosynthesis in microorganisms.
  Journal
FEMS Microbiol Lett 203:131-9 (2001)
DOI:10.1111/j.1574-6968.2001.tb10831.x
Other DBs
RHEA: 19644
LinkDB

KEGG   RCLASS: RC00131
Entry
RC00131                     RClass                                 
Definition
C5a-C6a:S2a+*-*+O6a:C2b+O5a-C2b+O6a
Reactant pair
C00223_C00811    C00323_C01197    C00406_C01494
C00411_C00482    C00423_C00540    C00423_C16256
C00511_C00894    C02214_C02411    C04114_C20748
C05619_C12203    C16461_C16465    C21283_C22207
Related class
Reaction
R01616 R01943 R02194 R02221 R02255 R03884 R05509 R05744
R06583 R07796 R08097 R10643 R11206 R12492 R12493 R13454
Enzyme
2.8.3.12        2.8.3.17        2.8.3.21        2.8.3.23        
2.8.3.-         6.2.1.12        6.2.1.34
Pathway
rn00130  Ubiquinone and other terpenoid-quinone biosynthesis
rn00643  Styrene degradation
rn00907  Pinene, camphor and geraniol degradation
rn00920  Sulfur metabolism
rn00940  Phenylpropanoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
Orthology
K01039  glutaconate CoA-transferase, subunit A [EC:2.8.3.12]
K01040  glutaconate CoA-transferase, subunit B [EC:2.8.3.12]
K01904  4-coumarate--CoA ligase [EC:6.2.1.12]
K08298  L-carnitine CoA-transferase [EC:2.8.3.21]
K13607  cinnamoyl-CoA:phenyllactate CoA-transferase [EC:2.8.3.17]
K28070  CoA transferase

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