KEGG   REACTION: R01739
Entry
R01739                      Reaction                               
Name
D-gluconate:NADP+ 2-oxidoreductase
Definition
D-Gluconic acid + NADP+ <=> 2-Keto-D-gluconic acid + NADPH + H+
Equation
C00257 + C00006 <=> C06473 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC00084  C00257_C06473
Enzyme
1.1.1.215
Pathway
rn00030  Pentose phosphate pathway
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.215
     R01739  D-Gluconic acid + NADP+ <=> 2-Keto-D-gluconic acid + NADPH + H+
Orthology
K00090  glyoxylate/hydroxypyruvate/2-ketogluconate reductase [EC:1.1.1.79 1.1.1.81 1.1.1.215]
K22229  2-ketogluconate reductase [EC:1.1.1.215]
Other DBs
RHEA: 16656
LinkDB

KEGG   RCLASS: RC00084
Entry
RC00084                     RClass                                 
Definition
C1c-C5a:*-*:C1c+C6a+O1a-C1c+C6a+O5a
Reactant pair
C00257_C06473    C00311_C05379    C00345_C01218
C00552_C03459    C00770_C15673    C00898_C03459
C01062_C02780    C02117_C02982    C03393_C06054
C04236_C04411    C05533_C05662    C21288_C21289
Related class
Reaction
R01739 R01741 R01742 R01899 R02032 R02034 R02545 R04210
R04426 R04862 R06180 R07151 R08879 R08880 R11336
Enzyme
1.1.1.42        1.1.1.43        1.1.1.85        1.1.1.87        
1.1.1.93        1.1.1.215       1.1.1.286       1.1.1.290       
1.1.1.397       1.1.3.27        1.1.99.3
Pathway
rn00020  Citrate cycle (TCA cycle)
rn00030  Pentose phosphate pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn00630  Glyoxylate and dicarboxylate metabolism
rn00750  Vitamin B6 metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
rn01240  Biosynthesis of cofactors
RModule
RM001  2-Oxocarboxylic acid chain extension by tricarboxylic acid pathway
Orthology
K00031  isocitrate dehydrogenase [EC:1.1.1.42]
K00032  phosphogluconate 2-dehydrogenase [EC:1.1.1.43]
K00052  3-isopropylmalate dehydrogenase [EC:1.1.1.85]
K00090  glyoxylate/hydroxypyruvate/2-ketogluconate reductase [EC:1.1.1.79 1.1.1.81 1.1.1.215]
K03473  erythronate-4-phosphate dehydrogenase [EC:1.1.1.290]
K05824  homoisocitrate dehydrogenase [EC:1.1.1.87]
K06151  gluconate 2-dehydrogenase alpha chain [EC:1.1.99.3]
K06152  gluconate 2-dehydrogenase gamma chain [EC:1.1.99.3]
K07246  tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase [EC:1.1.1.93 4.1.1.73 1.1.1.83]
K10978  methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]
K17753  isocitrate--homoisocitrate dehydrogenase [EC:1.1.1.286]
K21360  3-isopropylmalate/methylthioalkylmalate dehydrogenase [EC:1.1.1.85 1.1.1.-]
K22229  2-ketogluconate reductase [EC:1.1.1.215]

DBGET integrated database retrieval system