KEGG   REACTION: R01933
Entry
R01933                      Reaction                               
Name
2-oxoadipate dehydrogenase complex
Definition
2-Oxoadipate + CoA + NAD+ <=> Glutaryl-CoA + CO2 + NADH + H+
Equation
Comment
2-oxoglutarate dehydrogenase complex (see R08549)
multi-step reaction (see R01940+R02571+R07618)
Reaction class
RC00001  C00003_C00004
RC00004  C00010_C00527
RC02833  C00322_C00527
Enzyme
1.2.4.2         1.8.1.4         2.3.1.61
Pathway
rn00310  Lysine degradation
rn00380  Tryptophan metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Orthology
K00382  dihydrolipoamide dehydrogenase [EC:1.8.1.4]
K00658  2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
K15791  probable 2-oxoglutarate dehydrogenase E1 component DHKTD1 [EC:1.2.4.2]
Other DBs
RHEA: 30798
LinkDB

KEGG   RCLASS: RC02833
Entry
RC02833                     RClass                                 
Definition
C5a-C5a:C6a+*-*+S2a:C1b+O5a-C1b+O5a
Reactant pair
Related class
Reaction
Enzyme
1.2.1.105       1.2.4.2         1.2.4.4         1.2.7.1         
1.2.7.3         1.2.7.7         1.2.7.11        1.8.1.4         
2.3.1.54        2.3.1.61
Pathway
rn00020  Citrate cycle (TCA cycle)
rn00280  Valine, leucine and isoleucine degradation
rn00310  Lysine degradation
rn00380  Tryptophan metabolism
rn00640  Propanoate metabolism
rn00720  Carbon fixation pathways in prokaryotes
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
RModule
RM903  Oxidative decarboxylation of 2-oxoacid to form its CoA derivative
Orthology
K00164  2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
K00166  2-oxoisovalerate dehydrogenase E1 component alpha subunit [EC:1.2.4.4]
K00167  2-oxoisovalerate dehydrogenase E1 component beta subunit [EC:1.2.4.4]
K00169  pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
K00170  pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
K00171  pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
K00172  pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
K00174  2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
K00175  2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
K00176  2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]
K00177  2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]
K00186  2-oxoisovalerate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.7]
K00187  2-oxoisovalerate ferredoxin oxidoreductase beta subunit [EC:1.2.7.7]
K00188  2-oxoisovalerate ferredoxin oxidoreductase delta subunit [EC:1.2.7.7]
K00189  2-oxoisovalerate/pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.7 1.2.7.1]
K00382  dihydrolipoamide dehydrogenase [EC:1.8.1.4]
K00656  formate C-acetyltransferase [EC:2.3.1.54]
K00658  2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
K01616  multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
K11381  2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]
K15791  probable 2-oxoglutarate dehydrogenase E1 component DHKTD1 [EC:1.2.4.2]

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