KEGG   REACTION: R01936
Entry
R01936                      Reaction                               
Name
(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating)
Definition
Oxaloglutarate <=> 2-Oxoadipate + CO2
Equation
Comment
second step of R01934 (R04862 + R01936)
following after R04862
Reaction class
RC00626  C00322_C05533
Enzyme
1.1.1.87        1.1.1.286
Pathway
rn01210  2-Oxocarboxylic acid metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.87
     R01936  Oxaloglutarate <=> 2-Oxoadipate + CO2
    1.1.1.286
     R01936  Oxaloglutarate <=> 2-Oxoadipate + CO2
Orthology
K05824  homoisocitrate dehydrogenase [EC:1.1.1.87]
K10978  methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]
K17753  isocitrate--homoisocitrate dehydrogenase [EC:1.1.1.286]
LinkDB

KEGG   RCLASS: RC00626
Entry
RC00626                     RClass                                 
Definition
C1b-C1c:*-C6a:C1b+C5a-C1b+C5a
Reactant pair
Related class
Reaction
Enzyme
1.1.1.42        1.1.1.87        1.1.1.286       4.1.1.94        
6.4.1.3         6.4.1.7
Pathway
rn00020  Citrate cycle (TCA cycle)
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
RModule
RM001  2-Oxocarboxylic acid chain extension by tricarboxylic acid pathway
Orthology
K00031  isocitrate dehydrogenase [EC:1.1.1.42]
K05824  homoisocitrate dehydrogenase [EC:1.1.1.87]
K10978  methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]
K17753  isocitrate--homoisocitrate dehydrogenase [EC:1.1.1.286]

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