KEGG   REACTION: R02085
Entry
R02085                      Reaction                               
Name
(S)-3-Hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming)
Definition
(S)-3-Hydroxy-3-methylglutaryl-CoA <=> 3-Methylglutaconyl-CoA + H2O
Equation
C00356 <=> C03231 + C00001
Reaction class
RC02416  C00356_C03231
Enzyme
4.2.1.18
Pathway
rn00280  Valine, leucine and isoleucine degradation
rn01100  Metabolic pathways
Module
M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Orthology
K05607  methylglutaconyl-CoA hydratase [EC:4.2.1.18]
K13766  methylglutaconyl-CoA hydratase [EC:4.2.1.18]
Other DBs
RHEA: 21539
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