KEGG   REACTION: R02125
Entry
R02125                      Reaction                               
Name
retinal:oxygen oxidoreductase
Definition
Retinal + Oxygen + H2O <=> Retinoate + Hydrogen peroxide
Equation
C00376 + C00007 + C00001 <=> C00777 + C00027
Reaction class
RC00218  C00376_C00777
RC02755  C00007_C00027
Enzyme
1.2.3.1
Pathway
rn00830  Retinol metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.3  With oxygen as acceptor
    1.2.3.1
     R02125  Retinal + Oxygen + H2O <=> Retinoate + Hydrogen peroxide
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.2.3.1
   R00635  Aldehyde <=> Carboxylate
    R02125  Retinal <=> Retinoate
Orthology
K00157  aldehyde oxidase [EC:1.2.3.1]
Reference
1  [PMID:17992629]
  Authors
Graessler J, Fischer S.
  Title
The dual substrate specificity of aldehyde oxidase 1 for retinal and acetaldehyde and its role in ABCA1 mediated efflux.
  Journal
Horm Metab Res 39:775-6 (2007)
DOI:10.1055/s-2007-992126
Other DBs
RHEA: 22523
LinkDB

KEGG   RCLASS: RC00218
Entry
RC00218                     RClass                                 
Definition
C4a-C6a:*-O6a:C2b+O4a-C2b+O6a
Reactant pair
C00376_C00777    C00482_C05610    C00682_C02501
C01494_C02666    C01499_C16461    C02220_C03824
C03461_C16502    C04324_C04484    C06082_C13455
C06613_C06614    C06615_C16348    C13453_C13454
C15493_C16681
Related class
Reaction
R02123 R02125 R02762 R03889 R04453 R05237 R05238 R05700
R05701 R06955 R06957 R07441 R07442 R08086 R08146 R08384
R08385
Enzyme
1.2.1.3         1.2.1.32        1.2.1.36        1.2.1.68        
1.2.1.85        1.2.1.86        1.2.3.1         1.2.3.14
Pathway
rn00362  Benzoate degradation
rn00380  Tryptophan metabolism
rn00625  Chloroalkane and chloroalkene degradation
rn00830  Retinol metabolism
rn00906  Carotenoid biosynthesis
rn00907  Pinene, camphor and geraniol degradation
rn00940  Phenylpropanoid biosynthesis
rn00981  Insect hormone biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
RModule
RM009  Meta-cleavage of dihydroxylated aromatic ring
Orthology
K00128  aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00157  aldehyde oxidase [EC:1.2.3.1]
K07249  retinal dehydrogenase [EC:1.2.1.36]
K09842  abscisic-aldehyde oxidase [EC:1.2.3.14]
K10217  aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase [EC:1.2.1.32 1.2.1.85]
K12355  coniferyl-aldehyde dehydrogenase [EC:1.2.1.68]
K17832  geranial dehydrogenase [EC:1.2.1.86]
K23234  aminomuconate-semialdehyde dehydrogenase [EC:1.2.1.32]

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