KEGG   REACTION: R02197
Entry
R02197                      Reaction                               
Name
L-isoleucine:oxygen oxidoreductase (deaminating)
Definition
L-Isoleucine + H2O + Oxygen <=> (S)-3-Methyl-2-oxopentanoic acid + Ammonia + Hydrogen peroxide
Equation
C00407 + C00001 + C00007 <=> C00671 + C00014 + C00027
Reaction class
RC00036  C00407_C00671
RC02755  C00007_C00027
Enzyme
1.4.3.2
Pathway
rn00280  Valine, leucine and isoleucine degradation
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.4  Acting on the CH-NH2 group of donors
   1.4.3  With oxygen as acceptor
    1.4.3.2
     R02197  L-Isoleucine + H2O + Oxygen <=> (S)-3-Methyl-2-oxopentanoic acid + Ammonia + Hydrogen peroxide
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.4.3.2
   R01259  L-Amino acid <=> 2-Oxo acid
    R02197  L-Isoleucine <=> (S)-3-Methyl-2-oxopentanoic acid
Orthology
K03334  L-amino-acid oxidase [EC:1.4.3.2]
Other DBs
RHEA: 61235
LinkDB

KEGG   RCLASS: RC00036
Entry
RC00036                     RClass                                 
Definition
C1c-C5a:N1a+*-*+O5a:C1c+C6a-C1c+C6a
Reactant pair
C00141_C00183    C00407_C00671    C03618_C06030
C06054_C06055    C20646_C20895
Related class
Reaction
R01212 R01214 R01215 R01434 R02196 R02197 R02199 R02200
R04269 R05085 R10845
Enzyme
1.4.1.8         1.4.1.9         1.4.1.23        1.4.3.2         
2.6.1.6         2.6.1.32        2.6.1.42        2.6.1.52        
2.6.1.57        2.6.1.66        2.6.1.107
Pathway
rn00280  Valine, leucine and isoleucine degradation
rn00290  Valine, leucine and isoleucine biosynthesis
rn00660  C5-Branched dibasic acid metabolism
rn00750  Vitamin B6 metabolism
rn00770  Pantothenate and CoA biosynthesis
rn00966  Glucosinolate biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
rn01240  Biosynthesis of cofactors
RModule
RM044  2-Oxocarboxylic acid conversion to its CoA derivative
RM901  Reductive amination of 2-oxocarboxylic acid
Orthology
K00263  leucine dehydrogenase [EC:1.4.1.9]
K00271  valine dehydrogenase (NAD+) [EC:1.4.1.23]
K00826  branched-chain amino acid aminotransferase [EC:2.6.1.42]
K00831  phosphoserine aminotransferase [EC:2.6.1.52]
K00832  aromatic-amino-acid transaminase [EC:2.6.1.57]
K00835  valine--pyruvate aminotransferase [EC:2.6.1.66]
K03334  L-amino-acid oxidase [EC:1.4.3.2]
K14260  alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]

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