KEGG   REACTION: R02269
Entry
R02269                      Reaction                               
Name
5,6-dihydrouracil amidohydrolase
Definition
5,6-Dihydrouracil + H2O <=> 3-Ureidopropionate
Equation
C00429 + C00001 <=> C02642
Reaction class
RC00632  C00429_C02642
Enzyme
3.5.2.2
Pathway
rn00240  Pyrimidine metabolism
rn00410  beta-Alanine metabolism
rn00770  Pantothenate and CoA biosynthesis
rn01100  Metabolic pathways
Module
M00046  Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.2
     R02269  5,6-Dihydrouracil + H2O <=> 3-Ureidopropionate
Orthology
K01464  dihydropyrimidinase [EC:3.5.2.2]
Other DBs
RHEA: 16124
LinkDB

KEGG   RCLASS: RC00632
Entry
RC00632                     RClass                                 
Definition
C5x-C6a:N1x+*-*+O6a:C1x+O5x-C1b+O6a
N1x-N1a:C5x-*:C5x-C5a
Reactant pair
C00337_C00438    C00429_C02642    C00813_C15607
C01043_C02565
Related class
Reaction
R01993 R02139 R02269 R03187
Enzyme
3.5.2.1         3.5.2.2         3.5.2.3         3.5.2.14
Pathway
rn00240  Pyrimidine metabolism
rn00330  Arginine and proline metabolism
rn00410  beta-Alanine metabolism
rn00770  Pantothenate and CoA biosynthesis
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
RModule
RM024  Pyrimidine degradation
Orthology
K01464  dihydropyrimidinase [EC:3.5.2.2]
K01465  dihydroorotase [EC:3.5.2.3]
K01473  N-methylhydantoinase A [EC:3.5.2.14]
K01474  N-methylhydantoinase B [EC:3.5.2.14]
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
K19794  barbiturase [EC:3.5.2.1]

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