KEGG   REACTION: R02864
Entry
R02864                      Reaction                               
Name
S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase
Definition
Siroheme + 2 H+ <=> Fe2+ + Sirohydrochlorin
Equation
C00748 + 2 C00080 <=> C14818 + C05778
Comment
multifunctional enzyme: siroheme synthase: sirohydrochlorin ferrochelatase (R03194+R03947+R02864)
following after R03947
Reaction class
RC01012  C00748_C05778
Enzyme
4.99.1.4
Pathway
rn00860  Porphyrin metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01240  Biosynthesis of cofactors
Module
M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4
     R02864  Siroheme + 2 H+ <=> Fe2+ + Sirohydrochlorin
Orthology
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
K02304  precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:1.3.1.76 4.99.1.4]
K03794  sirohydrochlorin ferrochelatase [EC:4.99.1.4]
Other DBs
RHEA: 24363
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