KEGG   REACTION: R02869
Entry
R02869                      Reaction                               
Name
S-adenosylmethioninamine:spermidine 3-aminopropyltransferase
Definition
S-Adenosylmethioninamine + Spermidine <=> 5'-Methylthioadenosine + Spermine
Equation
C01137 + C00315 <=> C00170 + C00750
Reaction class
RC00021  C00170_C01137
RC00053  C00315_C00750
Enzyme
2.5.1.22
Pathway
rn00270  Cysteine and methionine metabolism
rn00330  Arginine and proline metabolism
rn00480  Glutathione metabolism
rn01100  Metabolic pathways
Orthology
K00802  spermine synthase [EC:2.5.1.22]
Other DBs
RHEA: 19976
LinkDB

KEGG   REACTION: R09076
Entry
R09076                      Reaction                               
Name
spermidine:oxygen oxidoreductase (spermidine-forming)
Definition
Spermine + Oxygen + H2O <=> Spermidine + 3-Aminopropanal + Hydrogen peroxide
Equation
C00750 + C00007 + C00001 <=> C00315 + C05665 + C00027
Reaction class
RC00053  C00315_C00750
RC00225  C00750_C05665
RC02755  C00007_C00027
Enzyme
1.5.3.16        1.5.3.17
Pathway
rn00330  Arginine and proline metabolism
rn00410  beta-Alanine metabolism
rn00770  Pantothenate and CoA biosynthesis
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00913  Pantothenate biosynthesis, 2-oxoisovalerate/spermine => pantothenate
Orthology
K12259  spermine oxidase [EC:1.5.3.16 1.5.3.-]
K13366  polyamine oxidase [EC:1.5.3.14 1.5.3.16 1.5.3.-]
K13367  polyamine oxidase [EC:1.5.3.17]
K17839  polyamine oxidase [EC:1.5.3.17 1.5.3.-]
Other DBs
RHEA: 25807
LinkDB

KEGG   RCLASS: RC00053
Entry
RC00053                     RClass                                 
Definition
N1a-N1b:*-C1b:C1b-C1b
Reactant pair
C00037_C17323    C00047_C16489    C00134_C00315
C00134_C00612    C00134_C06366    C00134_C18172
C00179_C20560    C00189_C06772    C00315_C00750
C00315_C00986    C00315_C02567    C00315_C19669
C00797_C11735    C00986_C01029    C00986_C03375
C00986_C18174    C01672_C16565    C01705_C11033
C03375_C21004    C07281_C07282    C11478_C17323
C16561_C16569    C21004_C21100
Related class
Reaction
R00018 R01914 R01915 R01919 R01920 R02869 R03271 R03899
R05329 R05381 R05863 R08125 R08296 R08359 R08701 R08702
R09074 R09075 R09076 R09077 R09079 R09080 R09531 R10338
R11088 R11089 R11486
Enzyme
1.4.3.19        1.5.1.43        1.5.3.13        1.5.3.14        
1.5.3.15        1.5.3.16        1.5.3.17        1.5.3.23        
1.5.3.-         1.5.99.6        2.5.1.16        2.5.1.22        
2.5.1.23        2.5.1.44        2.5.1.45        2.5.1.46        
2.5.1.79        2.5.1.104       2.5.1.126       2.5.1.127       
3.5.-.-         4.3.3.-
Pathway
rn00330  Arginine and proline metabolism
rn00410  beta-Alanine metabolism
rn00480  Glutathione metabolism
rn00564  Glycerophospholipid metabolism
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn00982  Drug metabolism - cytochrome P450
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K00308  N1-acetylpolyamine oxidase [EC:1.5.3.13]
K00316  spermidine dehydrogenase [EC:1.5.99.6]
K00797  spermidine synthase [EC:2.5.1.16]
K00802  spermine synthase [EC:2.5.1.22]
K00808  homospermidine synthase [EC:2.5.1.44]
K03495  tRNA uridine 5-carboxymethylaminomethyl modification enzyme
K03650  tRNA modification GTPase [EC:3.6.-.-]
K10708  fructoselysine 6-phosphate deglycase [EC:3.5.-.-]
K12259  spermine oxidase [EC:1.5.3.16 1.5.3.-]
K13366  polyamine oxidase [EC:1.5.3.14 1.5.3.16 1.5.3.-]
K13367  polyamine oxidase [EC:1.5.3.17]
K13746  carboxynorspermidine synthase [EC:1.5.1.43]
K15461  tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
K17839  polyamine oxidase [EC:1.5.3.17 1.5.3.-]
K24034  spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming) [EC:2.5.1.16 1.5.1.10]

KEGG   RCLASS: RC00225
Entry
RC00225                     RClass                                 
Definition
C1b-C4a:N1b+*-*+O4a:C1b-C1b
Reactant pair
C00232_C15987    C00315_C00555    C00315_C05665
C00441_C18172    C00441_C18174    C00449_C04076
C00612_C18170    C00750_C05665    C01029_C05936
C02567_C18170    C06754_C07047    C16608_C16612
C19567_C20361
Related class
Reaction
R01914 R01915 R02313 R02315 R03899 R08287 R08347 R09074
R09075 R09076 R09077 R09079 R09080 R09495 R10101 R10103
Enzyme
1.4.2.3         1.4.3.4         1.5.1.9         1.5.1.10        
1.5.1.43        1.5.3.13        1.5.3.14        1.5.3.15        
1.5.3.16        1.5.3.17        1.5.3.18        1.5.3.21        
1.5.99.6        1.14.14.1       1.14.14.-
Pathway
rn00300  Lysine biosynthesis
rn00310  Lysine degradation
rn00330  Arginine and proline metabolism
rn00410  beta-Alanine metabolism
rn00760  Nicotinate and nicotinamide metabolism
rn00770  Pantothenate and CoA biosynthesis
rn00982  Drug metabolism - cytochrome P450
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01230  Biosynthesis of amino acids
rn01240  Biosynthesis of cofactors
Orthology
K00274  monoamine oxidase [EC:1.4.3.4]
K00293  saccharopine dehydrogenase (NADP+, L-glutamate forming) [EC:1.5.1.10]
K00308  N1-acetylpolyamine oxidase [EC:1.5.3.13]
K00316  spermidine dehydrogenase [EC:1.5.99.6]
K12259  spermine oxidase [EC:1.5.3.16 1.5.3.-]
K13366  polyamine oxidase [EC:1.5.3.14 1.5.3.16 1.5.3.-]
K13367  polyamine oxidase [EC:1.5.3.17]
K13746  carboxynorspermidine synthase [EC:1.5.1.43]
K14157  alpha-aminoadipic semialdehyde synthase [EC:1.5.1.8 1.5.1.9]
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
K17690  cytochrome P450 family 3 subfamily A5 [EC:1.14.14.1]
K17709  cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-]
K17839  polyamine oxidase [EC:1.5.3.17 1.5.3.-]
K20155  4-methylaminobutanoate oxidase (methylamine-forming) [EC:1.5.3.21]
K20158  pseudooxynicotine dehydrogenase [EC:1.4.2.3]
K24034  spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming) [EC:2.5.1.16 1.5.1.10]

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