KEGG   REACTION: R03915
Entry
R03915                      Reaction                               
Name
glutathione:protein-disulfide oxidoreductase
Definition
Protein dithiol + Glutathione disulfide <=> Protein disulfide + 2 Glutathione
Equation
C02315 + C00127 <=> C02582 + 2 C00051
Reaction class
RC00011  C00051_C00127
RC00013  C02315_C02582
Enzyme
1.8.4.2
Pathway
rn00480  Glutathione metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.8  Acting on a sulfur group of donors
   1.8.4  With a disulfide as acceptor
    1.8.4.2
     R03915  Protein dithiol + Glutathione disulfide <=> Protein disulfide + 2 Glutathione
Orthology
K05360  protein-disulfide reductase (glutathione) [EC:1.8.4.2]
Other DBs
RHEA: 21067
LinkDB

KEGG   REACTION: R02824
Entry
R02824                      Reaction                               
Name
glutathione:insulin oxidoreductase
Definition
Insulin + 2 Glutathione <=> Reduced insulin + Glutathione disulfide
Equation
C00723 + 2 C00051 <=> C02288 + C00127
Reaction class
RC00011  C00051_C00127
Enzyme
1.8.4.2
Pathway
rn00480  Glutathione metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.8  Acting on a sulfur group of donors
   1.8.4  With a disulfide as acceptor
    1.8.4.2
     R02824  Insulin + 2 Glutathione <=> Reduced insulin + Glutathione disulfide
Orthology
K05360  protein-disulfide reductase (glutathione) [EC:1.8.4.2]
LinkDB

KEGG   RCLASS: RC00011
Entry
RC00011                     RClass                                 
Definition
S1a-S3a:*-S3a:C1b-C1b
Reactant pair
C00010_C00920    C00010_C02015    C00051_C00127
C00051_C00920    C00051_C05526    C00097_C00491
C00097_C05526    C00155_C01817    C00669_C03646
C00736_C01420    C03576_C04832    C04628_C04832
C06717_C11502    C19689_C19690    C21736_C21737
Related class
Reaction
R00091 R00094 R00115 R00120 R00274 R00892 R00900 R01108
R01109 R01110 R01111 R01113 R01292 R01875 R02409 R02742
R02824 R03167 R03915 R03984 R04039 R04540 R04541 R04860
R05714 R05715 R05716 R07175 R09368 R09561 R09563 R11876
R11928 R11931 R11943 R11944 R12578
Enzyme
1.5.4.1         1.8.1.6         1.8.1.7         1.8.1.9         
1.8.1.10        1.8.1.13        1.8.1.14        1.8.1.15        
1.8.1.16        1.8.1.20        1.8.3.3         1.8.4.1         
1.8.4.2         1.8.4.3         1.8.4.4         1.8.4.7         
1.8.5.1         1.8.7.3         1.8.98.1        1.8.98.4        
1.8.98.5        1.8.98.6        1.11.1.9        1.11.1.12       
1.11.1.17       1.11.1.27       2.8.1.3         2.8.4.1
Pathway
rn00270  Cysteine and methionine metabolism
rn00480  Glutathione metabolism
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Orthology
K00125  formate dehydrogenase (coenzyme F420) beta subunit [EC:1.17.98.3 1.8.98.6]
K00310  pyrimidodiazepine synthase [EC:1.5.4.1]
K00383  glutathione reductase (NADPH) [EC:1.8.1.7]
K00399  methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
K00401  methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
K00402  methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
K00432  glutathione peroxidase [EC:1.11.1.9]
K03388  heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
K03389  heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
K03390  heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
K03423  bis-gamma-glutamylcystine reductase [EC:1.8.1.13]
K05360  protein-disulfide reductase (glutathione) [EC:1.8.4.2]
K05361  phospholipid-hydroperoxide glutathione peroxidase [EC:1.11.1.12]
K08264  heterodisulfide reductase subunit D [EC:1.8.98.1]
K08265  heterodisulfide reductase subunit E [EC:1.8.98.1]
K11188  peroxiredoxin 6 [EC:1.11.1.7 1.11.1.27 3.1.1.-]
K14126  F420-non-reducing hydrogenase large subunit [EC:1.12.99.- 1.8.98.5]
K14127  F420-non-reducing hydrogenase iron-sulfur subunit [EC:1.12.99.- 1.8.98.5 1.8.98.6]
K14128  F420-non-reducing hydrogenase small subunit [EC:1.12.99.- 1.8.98.5]
K21888  glutathione dehydrogenase/transferase [EC:1.8.5.1 2.5.1.18]
K22480  heterodisulfide reductase subunit A1 [EC:1.8.7.3]
K22481  heterodisulfide reductase subunit B1 [EC:1.8.7.3]
K22482  heterodisulfide reductase subunit C1 [EC:1.8.7.3]
K22516  formate dehydrogenase (coenzyme F420) alpha subunit [EC:1.17.98.3 1.8.98.6]
K24136  glutathione-dependent peroxiredoxin [EC:1.11.1.27]
K24137  glutaredoxin/glutathione-dependent peroxiredoxin [EC:1.11.1.25 1.11.1.27]
K24138  glutaredoxin/glutathione-dependent peroxiredoxin [EC:1.11.1.25 1.11.1.27]

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