KEGG   REACTION: R03968
Entry
R03968                      Reaction                               
Name
2-isopropylmalate hydro-lyase
Definition
alpha-Isopropylmalate <=> 2-Isopropylmaleate + H2O
Equation
Reaction class
RC01041  C02504_C02631
Enzyme
Pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
Module
M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33
     R03968  alpha-Isopropylmalate <=> 2-Isopropylmaleate + H2O
Orthology
K01702  3-isopropylmalate dehydratase [EC:4.2.1.33]
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
K01704  3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
K21359  3-isopropylmalate/methylthioalkylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.170]
Other DBs
RHEA: 16296
LinkDB

KEGG   RCLASS: RC01041
Entry
RC01041                     RClass                                 
Definition
C1b-C2b:*-*:C1d+C6a-C2c+C6a
C1d-C2c:O1a-*:C1b+C1c+C6a-C2b+C1c+C6a
Reactant pair
Related class
Reaction
Enzyme
Pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
RModule
RM001  2-Oxocarboxylic acid chain extension by tricarboxylic acid pathway
Orthology
K01702  3-isopropylmalate dehydratase [EC:4.2.1.33]
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
K01704  3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
K21359  3-isopropylmalate/methylthioalkylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.170]

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