KEGG   REACTION: R04001
Entry
R04001                      Reaction                               

Name
3-Isopropylmalate hydro-lyase
Definition
(2R,3S)-3-Isopropylmalate <=> 2-Isopropylmaleate + H2O
Equation
Reaction class
RC01046  C02631_C04411
Enzyme
Pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
Module
M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Orthology
K01702  3-isopropylmalate dehydratase [EC:4.2.1.33]
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
K01704  3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
K21359  3-isopropylmalate/methylthioalkylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.170]
Other DBs
RHEA: 10679
LinkDB

KEGG   RCLASS: RC01046
Entry
RC01046                     RClass                                 

Definition
C1c-C2b:O1a-*:C1c+C6a-C2c+C6a
C1c-C2c:*-*:C1c+C1c+C6a-C1c+C2b+C6a
Reactant pair
Related class
Reaction
Enzyme
Pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
RModule
RM001  2-Oxocarboxylic acid chain extension by tricarboxylic acid pathway
Orthology
K01702  3-isopropylmalate dehydratase [EC:4.2.1.33]
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
K01704  3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
K21359  3-isopropylmalate/methylthioalkylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.170]

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