KEGG   REACTION: R04198
Entry
R04198                      Reaction                               
Name
2,3,4,5-tetrahydrodipicolinate:NAD+ 4-oxidoreductase
Definition
2,3,4,5-Tetrahydrodipicolinate + NAD+ + H2O <=> (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate + NADH + H+
Equation
Comment
NADP+ (see R04199)
Reaction class
RC00001  C00003_C00004
RC00478  C03972_C20258
Enzyme
Pathway
rn00261  Monobactam biosynthesis
rn00300  Lysine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01230  Biosynthesis of amino acids
Module
M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
M00525  Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine
M00526  Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
M00527  Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Orthology
K00215  4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
Other DBs
RHEA: 35326
LinkDB

KEGG   REACTION: R04199
Entry
R04199                      Reaction                               
Name
2,3,4,5-tetrahydrodipicolinate:NADP+ 4-oxidoreductase
Definition
2,3,4,5-Tetrahydrodipicolinate + NADP+ + H2O <=> (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+
Equation
Comment
NAD+ (see R04198)
Reaction class
RC00001  C00005_C00006
RC00478  C03972_C20258
Enzyme
Pathway
rn00261  Monobactam biosynthesis
rn00300  Lysine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01230  Biosynthesis of amino acids
Module
M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
M00525  Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine
M00526  Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
M00527  Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Orthology
K00215  4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
Other DBs
RHEA: 35334
LinkDB

KEGG   RCLASS: RC00478
Entry
RC00478                     RClass                                 
Definition
C1x-C1y:*-O1a:C1x+C1x-C1x+C1x
Reactant pair
Related class
Reaction
Enzyme
1.14.11.2       1.14.11.13      1.14.11.56      1.14.11.57      
1.14.13.-       1.14.14.62      1.14.14.69      1.14.14.76      
1.14.15.3       1.14.15.24      1.14.-.-        1.17.1.8
Pathway
rn00261  Monobactam biosynthesis
rn00300  Lysine biosynthesis
rn00330  Arginine and proline metabolism
rn00904  Diterpenoid biosynthesis
rn00906  Carotenoid biosynthesis
rn00930  Caprolactam degradation
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01230  Biosynthesis of amino acids
Orthology
K00215  4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
K00472  prolyl 4-hydroxylase [EC:1.14.11.2]
K00496  alkane 1-monooxygenase [EC:1.14.15.3]
K02294  beta-carotene hydroxylase [EC:1.14.13.-]
K04125  gibberellin 2beta-dioxygenase [EC:1.14.11.13]
K15746  beta-carotene 3-hydroxylase [EC:1.14.15.24]
K15747  beta-ring hydroxylase [EC:1.14.-.-]
K16083  ent-isokaurene hydroxylase [EC:1.14.14.76]
K22492  beta-carotene 3-hydroxylase [EC:1.14.15.24]
K22634  salviol synthase [EC:1.14.14.62]
K23037  beta-carotene 4-ketolase/3-hydroxylase [EC:1.14.99.63 1.14.15.24 1.14.99.-]

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