KEGG   REACTION: R04439
Entry
R04439                      Reaction                               
Name
(R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)
Definition
(R)-2,3-Dihydroxy-3-methylbutanoate + NADP+ <=> (S)-2-Acetolactate + NADPH + H+
Equation
C04272 + C00006 <=> C06010 + C00005 + C00080
Comment
NAD+ (see R10916)
Reaction class
RC00001  C00005_C00006
RC00836  C04272_C06010
Enzyme
1.1.1.86        1.1.1.383
Pathway
rn00770  Pantothenate and CoA biosynthesis
rn01100  Metabolic pathways
Module
M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86
     R04439  (R)-2,3-Dihydroxy-3-methylbutanoate + NADP+ <=> (S)-2-Acetolactate + NADPH + H+
    1.1.1.383
     R04439  (R)-2,3-Dihydroxy-3-methylbutanoate + NADP+ <=> (S)-2-Acetolactate + NADPH + H+
Orthology
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Other DBs
RHEA: 22071
LinkDB

KEGG   RCLASS: RC00836
Entry
RC00836                     RClass                                 
Definition
C1a-C1a:C1d+*-*+C1d:*-*
C1c-C1d:*-C1a:C1d+C6a+O1a-C5a+C6a+O1a
C1d-C5a:C1a-*:C1a+C1c+O1a-C1a+C1d+O5a
Reactant pair
C00900_C04039    C04272_C06010
Related class
Reaction
R03051 R04439 R10916
Enzyme
1.1.1.86        1.1.1.382       1.1.1.383
Pathway
rn00770  Pantothenate and CoA biosynthesis
Orthology
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]

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