KEGG   REACTION: R04737
Entry
R04737                      Reaction                               
Name
(S)-3-hydroxyhexadecanoyl-CoA:NAD+ oxidoreductase
Definition
(S)-3-Hydroxyhexadecanoyl-CoA + NAD+ <=> 3-Oxopalmitoyl-CoA + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00029  C05258_C05259
Enzyme
1.1.1.35        1.1.1.211
Pathway
rn00062  Fatty acid elongation
rn00071  Fatty acid degradation
rn01100  Metabolic pathways
rn01212  Fatty acid metabolism
Module
M00085  Fatty acid elongation in mitochondria
M00087  beta-Oxidation
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.35
     R04737  (S)-3-Hydroxyhexadecanoyl-CoA + NAD+ <=> 3-Oxopalmitoyl-CoA + NADH + H+
    1.1.1.211
     R04737  (S)-3-Hydroxyhexadecanoyl-CoA + NAD+ <=> 3-Oxopalmitoyl-CoA + NADH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.1.1.35
   R01778  (3S)-3-Hydroxyacyl-CoA <=> 3-Oxoacyl-CoA
    R04737  (S)-3-Hydroxyhexadecanoyl-CoA <=> 3-Oxopalmitoyl-CoA
  1.1.1.211
   R01778  (3S)-3-Hydroxyacyl-CoA <=> 3-Oxoacyl-CoA
    R04737  (S)-3-Hydroxyhexadecanoyl-CoA <=> 3-Oxopalmitoyl-CoA
Orthology
K00022  3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
K01782  3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
K01825  3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
K07514  enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
K07515  enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
K07516  3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
K10527  enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35 1.1.1.211]
Other DBs
RHEA: 31162
LinkDB

KEGG   RCLASS: RC00029
Entry
RC00029                     RClass                                 
Definition
C1c-C5a:*-*:C1b+C1b+O1a-C1b+C1b+O5a
Reactant pair
Related class
Reaction
Enzyme
1.1.1.6         1.1.1.8         1.1.1.35        1.1.1.94        
1.1.1.100       1.1.1.101       1.1.1.108       1.1.1.156       
1.1.1.157       1.1.1.211       1.1.1.254       1.1.1.259       
1.1.1.261       1.1.1.279       1.1.1.280       1.1.1.330       
1.1.1.-         1.1.3.21        1.1.5.3         1.1.99.22       
2.3.1.85        2.3.1.86        2.3.1.-
Pathway
rn00061  Fatty acid biosynthesis
rn00062  Fatty acid elongation
rn00071  Fatty acid degradation
rn00074  Mycolic acid biosynthesis
rn00253  Tetracycline biosynthesis
rn00360  Phenylalanine metabolism
rn00362  Benzoate degradation
rn00561  Glycerolipid metabolism
rn00564  Glycerophospholipid metabolism
rn00565  Ether lipid metabolism
rn00780  Biotin metabolism
rn00930  Caprolactam degradation
rn01056  Biosynthesis of type II polyketide backbone
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01212  Fatty acid metabolism
rn01240  Biosynthesis of cofactors
RModule
RM018  Beta oxidation in acyl-CoA degradation
RM020  Fatty acid synthesis using acetyl-CoA (reversal of RM018)
RM021  Fatty acid synthesis using malonyl-CoA
Orthology
K00005  glycerol dehydrogenase [EC:1.1.1.6]
K00006  glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8]
K00022  3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
K00057  glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
K00059  3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
K00074  3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
K00096  glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
K00105  alpha-glycerophosphate oxidase [EC:1.1.3.21]
K00111  glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]
K00112  glycerol-3-phosphate dehydrogenase subunit B [EC:1.1.5.3]
K00113  glycerol-3-phosphate dehydrogenase subunit C
K00665  fatty acid synthase, animal type [EC:2.3.1.85]
K00667  fatty acid synthase subunit alpha, fungi type [EC:2.3.1.86]
K01782  3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
K01825  3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
K06123  1-acylglycerone phosphate reductase [EC:1.1.1.101]
K07514  enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
K07515  enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
K07516  3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
K10251  17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K10527  enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35 1.1.1.211]
K11533  fatty acid synthase, bacteria type [EC:2.3.1.-]
K11539  carbonyl reductase 4 / 3-oxoacyl-[acyl-carrier protein] reductase beta subunit [EC:1.1.1.-]
K11610  meromycolic acid 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.-]
K12405  (3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.- 4.2.1.107 4.2.1.119]
K12420  ketoreductase [EC:1.1.1.-]
K18097  glycerol 2-dehydrogenase (NADP+) [EC:1.1.1.156]
K22251  glycerol dehydrogenase [EC:1.1.1.6]

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