REACTION: R04854
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Entry
R04854 Reaction
Name
20alpha-Hydroxycholesterol:oxygen oxidoreductase (side-chain-cleaving)
Definition
20alpha-Hydroxycholesterol + Oxygen + 2 Reduced adrenal ferredoxin + 2 H+ <=> 20alpha,22beta-Dihydroxycholesterol + H2O + 2 Oxidized adrenal ferredoxin
Equation
C05500
+
C00007
+ 2
C00662
+ 2
C00080
<=>
C05501
+
C00001
+ 2
C00667
Comment
second step of
R02724
(
R01454+R04854+R03933
)
Reaction class
RC01223
C05500_C05501
Enzyme
1.14.15.6
Pathway
rn00140
Steroid hormone biosynthesis
rn01100
Metabolic pathways
Module
M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Orthology
K00498
cholesterol monooxygenase (side-chain-cleaving) [EC:
1.14.15.6
]
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