KEGG   REACTION: R04863
Entry
R04863                      Reaction                               
Name
L-2-aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase
Definition
L-2-Aminoadipate adenylate + Holo-Lys2 <=> alpha-Aminoadipoyl-S-acyl enzyme + AMP
Equation
Comment
The second step of three-step reaction (R03098 + R04863 + R04390)
For reverse direction, one-step reaction (see R03103)
Reaction class
RC00039  C05535_C11482
RC00070  C00020_C05560
RC02816  C05535_C05560
Enzyme
Pathway
rn00300  Lysine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
Orthology
K00143  L-2-aminoadipate reductase [EC:1.2.1.95]
LinkDB

KEGG   RCLASS: RC02816
Entry
RC02816                     RClass                                 
Definition
C5a-C7a:S2a+*-*+O7a:C1b+O5a-C1b+O6a
Reactant pair
Related class
Reaction
Enzyme
1.2.1.95        2.3.1.8         2.3.1.19        2.3.1.21        
2.3.1.222       6.2.1.1         6.2.1.11        6.2.1.17
Pathway
rn00071  Fatty acid degradation
rn00300  Lysine biosynthesis
rn00640  Propanoate metabolism
rn00650  Butanoate metabolism
rn00780  Biotin metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01212  Fatty acid metabolism
Orthology
K00143  L-2-aminoadipate reductase [EC:1.2.1.95]
K00625  phosphate acetyltransferase [EC:2.3.1.8]
K00634  phosphate butyryltransferase [EC:2.3.1.19]
K01895  acetyl-CoA synthetase [EC:6.2.1.1]
K01908  propionyl-CoA synthetase [EC:6.2.1.17]
K08765  carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K08766  carnitine O-palmitoyltransferase 2 [EC:2.3.1.21]
K13788  phosphate acetyltransferase [EC:2.3.1.8]
K13923  phosphate propanoyltransferase [EC:2.3.1.222]
K15024  putative phosphotransacetylase [EC:2.3.1.8]
K19523  carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524  carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]

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