KEGG   REACTION: R05030
Entry
R05030                      Reaction                               
Name
beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphospho-ditrans,octacis-undecaprenol:L-glutamine amidoligase (ADP-forming)
Definition
ATP + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + Ammonia <=> ADP + Orthophosphate + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine
Equation
Comment
multi-step reaction (see R00256+R12330+R12331)
Reaction class
RC00002  C00002_C00008
RC00358  C05893_C05894
Enzyme
Pathway
rn00550  Peptidoglycan biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.13
     R05030  ATP + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + Ammonia <=> ADP + Orthophosphate + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine
Orthology
K07009  lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13]
K23393  lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13]
LinkDB

KEGG   RCLASS: RC00358
Entry
RC00358                     RClass                                 
Definition
C5a-C6a:N1a+*-*+O6a:C1c+O5a-C1c+O6a
Reactant pair
Related class
Reaction
Enzyme
3.5.1.57        3.5.1.86        6.3.1.14        6.3.5.13        
6.3.5.-
Pathway
rn00550  Peptidoglycan biosynthesis
rn00627  Aminobenzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K06927  diphthine-ammonia ligase [EC:6.3.1.14]
K07009  lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13]
K18541  mandelamide amidase [EC:3.5.1.86]
K23393  lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13]

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