KEGG   REACTION: R05064
Entry
R05064                      Reaction                               
Name
(S)-3-hydroxyisobutyryl-CoA hydrolase
Definition
(S)-3-Hydroxyisobutyryl-CoA + H2O <=> CoA + (S)-3-Hydroxyisobutyrate
Equation
C06000 + C00001 <=> C00010 + C06001
Reaction class
RC00004  C00010_C06000
RC00137  C06000_C06001
Enzyme
3.1.2.4
Pathway
rn00280  Valine, leucine and isoleucine degradation
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.1  Acting on ester bonds
   3.1.2  Thioester hydrolases
    3.1.2.4
     R05064  (S)-3-Hydroxyisobutyryl-CoA + H2O <=> CoA + (S)-3-Hydroxyisobutyrate
Orthology
K05605  3-hydroxyisobutyryl-CoA hydrolase [EC:3.1.2.4]
Other DBs
RHEA: 31254
LinkDB

KEGG   RCLASS: RC00137
Entry
RC00137                     RClass                                 
Definition
C5a-C6a:S2a+*-*+O6a:C1c+O5a-C1c+O6a
Reactant pair
C00082_C12461    C00186_C00827    C00256_C03451
C00683_C02170    C01188_C04047    C01213_C02170
C02630_C03058    C02929_C03899    C03264_C21089
C03964_C22205    C04554_C04644    C04554_C17345
C04722_C04760    C04722_C15613    C05607_C16257
C06000_C06001    C09816_C09817    C14115_C14116
C21096_C21098    C22006_C22206
Related class
Reaction
R01449 R01736 R02764 R03352 R03383 R04000 R04090 R04507
R04580 R05064 R05508 R05588 R06751 R06904 R07796 R08733
R08738 R11084 R11462 R12492 R12493
Enzyme
2.8.3.1         2.8.3.12        2.8.3.15        2.8.3.17        
2.8.3.24        2.8.3.-         3.1.2.4         3.1.2.6         
3.1.2.17        6.2.1.7         6.2.1.28        6.2.1.46        
6.2.1.-
Pathway
rn00120  Primary bile acid biosynthesis
rn00280  Valine, leucine and isoleucine degradation
rn00401  Novobiocin biosynthesis
rn00620  Pyruvate metabolism
rn00623  Toluene degradation
rn00626  Naphthalene degradation
rn00640  Propanoate metabolism
rn00643  Styrene degradation
rn00650  Butanoate metabolism
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
RModule
RM015  Methyl to carboxyl conversion on aromatic ring, anaerobic
RM019  Acyl-CoA conversion via dicarboxylate semialdehyde
Orthology
K01026  propionate CoA-transferase [EC:2.8.3.1]
K01039  glutaconate CoA-transferase, subunit A [EC:2.8.3.12]
K01040  glutaconate CoA-transferase, subunit B [EC:2.8.3.12]
K01069  hydroxyacylglutathione hydrolase [EC:3.1.2.6]
K05605  3-hydroxyisobutyryl-CoA hydrolase [EC:3.1.2.4]
K07543  benzylsuccinate CoA-transferase BbsE subunit [EC:2.8.3.15]
K07544  benzylsuccinate CoA-transferase BbsF subunit [EC:2.8.3.15]
K08748  solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7]
K12701  novobiocin biosynthesis protein NovH
K13607  cinnamoyl-CoA:phenyllactate CoA-transferase [EC:2.8.3.17]
K15569  naphthyl-2-methylsuccinate CoA transferase subunit [EC:2.8.3.-]
K15570  naphthyl-2-methylsuccinate CoA transferase subunit [EC:2.8.3.-]
K15646  coronamic acid synthetase CmaA, adenylation and thiolation didomain protein [EC:6.2.1.46]
K18660  malonyl-CoA/methylmalonyl-CoA synthetase [EC:6.2.1.76 6.2.1.-]
K18661  malonyl-CoA/methylmalonyl-CoA synthetase [EC:6.2.1.76 6.2.1.-]
K20882  (R)-2-hydroxy-4-methylpentanoate CoA-transferase [EC:2.8.3.24]

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