Entry |
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Name |
erythromycin-D,NADPH:oxygen oxidoreductase (12-hydroxylating)
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Definition |
Erythromycin D + NADPH + H+ + Oxygen <=> Erythromycin C + NADP+ + H2O
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Equation |
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 |
Comment |
1200-1900-fold preference for erythromycin D over the alternative substrate erythromycin B
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Reaction class |
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Enzyme |
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Pathway |
rn00522 | Biosynthesis of 12-, 14- and 16-membered macrolides |
rn01110 | Biosynthesis of secondary metabolites |
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Module |
M00774 | Erythromycin biosynthesis, propanoyl-CoA + methylmalonyl-CoA => deoxyerythronolide B => erythromycin A/B |
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Orthology |
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Other DBs |
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LinkDB |
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