KEGG   REACTION: R05692
Entry
R05692                      Reaction                               
Name
GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing)
Definition
GDP-L-fucose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+
Equation
C00325 + C00006 <=> C01222 + C00005 + C00080
Comment
two-step reaction (see R07059 + R07060), bifunctional enzyme
Reaction class
RC00001  C00005_C00006
RC01014  C00325_C01222
Enzyme
1.1.1.271
Pathway
rn00051  Fructose and mannose metabolism
rn00520  Amino sugar and nucleotide sugar metabolism
rn00541  O-Antigen nucleotide sugar biosynthesis
rn01100  Metabolic pathways
rn01250  Biosynthesis of nucleotide sugars
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.271
     R05692  GDP-L-fucose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+
Orthology
K02377  GDP-L-fucose synthase [EC:1.1.1.271]
Other DBs
RHEA: 18888
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