KEGG   REACTION: R05692
Entry
R05692                      Reaction                               
Name
GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing)
Definition
GDP-L-fucose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+
Equation
C00325 + C00006 <=> C01222 + C00005 + C00080
Comment
two-step reaction (see R07059+R07060), bifunctional enzyme
Reaction class
RC00001  C00005_C00006
RC01014  C00325_C01222
Enzyme
1.1.1.271
Pathway
rn00051  Fructose and mannose metabolism
rn00541  Biosynthesis of various nucleotide sugars
rn01100  Metabolic pathways
rn01250  Biosynthesis of nucleotide sugars
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.271
     R05692  GDP-L-fucose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+
Orthology
K02377  GDP-L-fucose synthase [EC:1.1.1.271]
Other DBs
RHEA: 18888
LinkDB

KEGG   RCLASS: RC01014
Entry
RC01014                     RClass                                 
Definition
C1y-C1y:*-*:C1a+C1y+O2x-C1a+C5x+O2x
C1y-C1y:*-*:C1y+C1y+O1a-C1y+C5x+O1a
C1y-C5x:*-*:C1y+C1y+O1a-C1y+C1y+O5x
Reactant pair
C00325_C01222    C02199_C04089    C03319_C11907
Related class
Reaction
R03879 R05692 R08935
Enzyme
1.1.1.271       1.1.1.-
Pathway
rn00051  Fructose and mannose metabolism
rn00523  Polyketide sugar unit biosynthesis
rn00541  Biosynthesis of various nucleotide sugars
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01250  Biosynthesis of nucleotide sugars
Orthology
K02377  GDP-L-fucose synthase [EC:1.1.1.271]
K12451  3,5-epimerase/4-reductase [EC:5.1.3.- 1.1.1.-]

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