KEGG   REACTION: R06746
Entry
R06746                      Reaction                               
Name
L-proline:[peptidyl-carrier protein] ligase (AMP-forming)
Definition
L-Proline + Peptidyl-carrier protein + ATP <=> L-Prolyl-[pcp] + AMP + Diphosphate
Equation
C00148 + C21097 + C00002 <=> C12470 + C00020 + C00013
Comment
two-step reaction (see R12056+R12057)
Reaction class
RC00039  C12470_C21097
RC01438  C00148_C12470
Enzyme
6.2.1.53
Pathway
rn00333  Prodigiosin biosynthesis
rn00401  Novobiocin biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
M00838  Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.53
     R06746  L-Proline + Peptidyl-carrier protein + ATP <=> L-Prolyl-[pcp] + AMP + Diphosphate
Orthology
K12719  L-proline---[L-prolyl-carrier protein] ligase [EC:6.2.1.53]
K12720  peptidyl carrier protein
K21780  L-proline---[L-prolyl-carrier protein] ligase [EC:6.2.1.53]
K21781  peptidyl carrier protein
LinkDB

KEGG   REACTION: R12056
Entry
R12056                      Reaction                               
Definition
ATP + L-Proline <=> Diphosphate + (L-Prolyl)adenylate
Equation
C00002 + C00148 <=> C00013 + C20656
Comment
the first step of the two-step reaction (see R06746, R12056+R12057)
Reaction class
RC00043  C00148_C20656
Enzyme
6.2.1.53
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.53
     R12056  ATP + L-Proline <=> Diphosphate + (L-Prolyl)adenylate
Orthology
K12719  L-proline---[L-prolyl-carrier protein] ligase [EC:6.2.1.53]
K12720  peptidyl carrier protein
K21780  L-proline---[L-prolyl-carrier protein] ligase [EC:6.2.1.53]
K21781  peptidyl carrier protein
Other DBs
RHEA: 11659
LinkDB

KEGG   REACTION: R12057
Entry
R12057                      Reaction                               
Definition
(L-Prolyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Prolyl-[pcp]
Equation
C20656 + C21097 <=> C00020 + C12470
Comment
the second step of the two-step reaction (see R06746, R12056+R12057)
Reaction class
RC00039  C12470_C21097
Enzyme
6.2.1.53
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.53
     R12057  (L-Prolyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Prolyl-[pcp]
Orthology
K12719  L-proline---[L-prolyl-carrier protein] ligase [EC:6.2.1.53]
K12720  peptidyl carrier protein
K21780  L-proline---[L-prolyl-carrier protein] ligase [EC:6.2.1.53]
K21781  peptidyl carrier protein
Other DBs
RHEA: 56283
LinkDB

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