KEGG   REACTION: R07509
Entry
R07509                      Reaction                               
Name
14-demethyllanosterol,ferrocytochrome-b5:oxygen oxidoreductase (hydroxylating)
Definition
14-Demethyllanosterol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 4alpha-Methylzymosterol-4-carboxylate + 6 Ferricytochrome b5 + 4 H2O
Equation
C05108 + 6 C00999 + 3 C00007 + 6 C00080 <=> C15808 + 6 C00996 + 4 C00001
Reaction class
RC00001  C00005_C00006
RC01952  C05108_C15808
Enzyme
1.14.18.9
Pathway
rn00100  Steroid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00101  Cholesterol biosynthesis, FPP => cholesterol
M00102  Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.18  With another compound as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.18.9
     R07509  14-Demethyllanosterol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 4alpha-Methylzymosterol-4-carboxylate + 6 Ferricytochrome b5 + 4 H2O
Orthology
K07750  methylsterol monooxygenase [EC:1.14.18.9]
LinkDB

KEGG   RCLASS: RC01952
Entry
RC01952                     RClass                                 
Definition
C1a-C6a:*+*-O6a+O6a:C1z-C1z
Reactant pair
C02283_C19943    C04530_C04840    C05108_C15808
C06090_C11874    C08616_C17148    C08830_C22116
C09092_C09163    C18224_C20208    C18225_C20149
C21796_C21818    C22103_C22106
Related class
Reaction
R07509 R09865 R09921 R10057 R10066 R10316 R10924 R11973
R11989 R12360 R12377
Enzyme
1.14.13.246     1.14.14.61      1.14.14.86      1.14.14.111     
1.14.14.115     1.14.14.126     1.14.18.9       1.14.18.10
Pathway
rn00100  Steroid biosynthesis
rn00904  Diterpenoid biosynthesis
rn00999  Biosynthesis of various plant secondary metabolites
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K04122  ent-kaurene oxidase [EC:1.14.14.86]
K07750  methylsterol monooxygenase [EC:1.14.18.9]
K14423  plant 4,4-dimethylsterol C-4alpha-methyl-monooxygenase [EC:1.14.18.10]
K16085  9beta-pimara-7,15-diene oxidase [EC:1.14.14.111]
K20667  beta-amyrin 28-monooxygenase [EC:1.14.14.126]
K21292  ent-kaurene oxidase [EC:1.14.14.86]
K22638  carnosic acid synthase [EC:1.14.14.61]

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