KEGG REACTION: R08101

REACTION: R08101

Entry

R08101                      Reaction

Name

2-fluorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)

Definition

2-Fluorobenzoate + NADH + H+ + Oxygen <=> 6-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+

Equation

C02359 + C00004 + C00080 + C00007 <=> C16481 + C00003

Reaction class

RC00001

C00003_C00004

RC01378

C02359_C16481

Enzyme

1.14.12.10

Pathway

rn00364

Fluorobenzoate degradation

rn01120

Microbial metabolism in diverse environments

rn01220

Degradation of aromatic compounds

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.10
     R08101  2-Fluorobenzoate + NADH + H+ + Oxygen <=> 6-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+

Orthology

K05549

benzoate/toluate 1,2-dioxygenase subunit alpha [EC:1.14.12.10 1.14.12.-]

K05550

benzoate/toluate 1,2-dioxygenase subunit beta [EC:1.14.12.10 1.14.12.-]

K05784

benzoate/toluate 1,2-dioxygenase reductase component [EC:1.18.1.-]

LinkDB

RCLASS: RC01378

Entry

RC01378                     RClass

Definition

C1y-C8x:O1a-*:C1z+C2x-C8y+C8x
C1z-C8y:O1a-*:C1y+C2y+C6a-C8x+C8y+C6a

Reactant pair

C02359_C16481 C06731_C07215

Related class

Reaction

R05428 R08101

Enzyme

1.14.12.10 1.14.12.-

Pathway

rn00364

Fluorobenzoate degradation

rn00622

Xylene degradation

rn01100

Metabolic pathways