KEGG   REACTION: R08110
Entry
R08110                      Reaction                               
Name
4-fluorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)
Definition
4-Fluorobenzoate + NADH + H+ + Oxygen <=> 4-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
Equation
C02371 + C00004 + C00080 + C00007 <=> C16480 + C00003
Reaction class
RC00001  C00003_C00004
RC00270  C02371_C16480
Enzyme
1.14.12.10
Pathway
rn00364  Fluorobenzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.10
     R08110  4-Fluorobenzoate + NADH + H+ + Oxygen <=> 4-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
Orthology
K05549  benzoate/toluate 1,2-dioxygenase subunit alpha [EC:1.14.12.10 1.14.12.-]
K05550  benzoate/toluate 1,2-dioxygenase subunit beta [EC:1.14.12.10 1.14.12.-]
K05784  benzoate/toluate 1,2-dioxygenase reductase component [EC:1.18.1.-]
LinkDB

KEGG   RCLASS: RC00270
Entry
RC00270                     RClass                                 
Definition
C1y-C8x:O1a-*:C1z+C2x-C8y+C8x
C1z-C8y:O1a-*:C1y+C2x+C6a-C8x+C8x+C6a
Reactant pair
C00180_C04634    C00180_C06321    C01454_C06729
C02364_C16479    C02371_C16480    C06318_C06337
Related class
Reaction
R05148 R05290 R05291 R05621 R05622 R07188 R08109 R08110
Enzyme
1.14.12.10      1.14.12.15      1.14.12.-
Pathway
rn00362  Benzoate degradation
rn00364  Fluorobenzoate degradation
rn00622  Xylene degradation
rn00624  Polycyclic aromatic hydrocarbon degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
RModule
RM005  Dihydroxylation of aromatic ring, type 1a (dioxygenase and decarboxylating dehydrogenase reactions)
Orthology
K05549  benzoate/toluate 1,2-dioxygenase subunit alpha [EC:1.14.12.10 1.14.12.-]
K05550  benzoate/toluate 1,2-dioxygenase subunit beta [EC:1.14.12.10 1.14.12.-]
K05784  benzoate/toluate 1,2-dioxygenase reductase component [EC:1.18.1.-]
K18074  terephthalate 1,2-dioxygenase oxygenase component alpha subunit [EC:1.14.12.15]
K18075  terephthalate 1,2-dioxygenase oxygenase component beta subunit [EC:1.14.12.15]
K18077  terephthalate 1,2-dioxygenase reductase component [EC:1.18.1.-]

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