KEGG   REACTION: R08249
Entry
R08249                      Reaction                               
Name
N-acetylisoniazid amidohydrolase
Definition
N-Acetylisoniazid + H2O <=> Acetylhydrazine + Isonicotinic acid
Equation
Comment
hepatic amidase
carboxylesterases (ec 3.1.1.1) also have some amidohydrolase activities
Reaction class
RC00162  C07446_C07585
RC00962  C07447_C07585
Enzyme
3.1.1.1         3.5.1.-
Pathway
rn00983  Drug metabolism - other enzymes
Orthology
K01044  carboxylesterase 1 [EC:3.1.1.1]
LinkDB

KEGG   RCLASS: RC00162
Entry
RC00162                     RClass                                 
Definition
C5a-C6a:N1b+*-*+O6a:C8y+O5a-C8y+O6a
Reactant pair
Related class
Reaction
Enzyme
3.1.1.1         3.5.1.32        3.5.1.40        3.5.1.79        
3.5.1.-         6.3.1.15        6.3.2.6         6.3.2.12        
6.3.2.14        6.3.2.17
Pathway
rn00230  Purine metabolism
rn00401  Novobiocin biosynthesis
rn00760  Nicotinate and nicotinamide metabolism
rn00790  Folate biosynthesis
rn00983  Drug metabolism - other enzymes
rn01053  Biosynthesis of siderophore group nonribosomal peptides
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01240  Biosynthesis of cofactors
Orthology
K01044  carboxylesterase 1 [EC:3.1.1.1]
K01252  bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14]
K01451  hippurate hydrolase [EC:3.5.1.32]
K01587  phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]
K01923  phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
K01930  folylpolyglutamate synthase [EC:6.3.2.17]
K02362  enterobactin synthetase component D [EC:6.3.2.14 2.7.8.-]
K02363  2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71]
K02364  L-serine---[L-seryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.72]
K11754  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K12709  8-demethylnovobiocic acid synthase [EC:6.3.1.15]
K13713  fusion protein PurCD [EC:6.3.2.6 6.3.4.13]
K20457  dihydrofolate synthase [EC:6.3.2.12]
K22099  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K24102  dihydrofolate synthase / dihydropteroate synthase [EC:6.3.2.12 2.5.1.15]

KEGG   RCLASS: RC00962
Entry
RC00962                     RClass                                 
Definition
N1a-N1b:*-C5a:N1b-N1b
Reactant pair
Related class
Reaction
Enzyme
2.3.1.5         2.3.2.9         3.1.1.1         3.5.1.-
Pathway
rn00983  Drug metabolism - other enzymes
Orthology
K00622  arylamine N-acetyltransferase [EC:2.3.1.5]
K01044  carboxylesterase 1 [EC:3.1.1.1]

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