KEGG   REACTION: R08566
Entry
R08566                      Reaction                               
Name
4-methyl-2-oxopentanoate:ferredoxin oxidoreductase (decarboxylating; CoA-3-methylbutanoylating)
Definition
4-Methyl-2-oxopentanoate + CoA + 2 Oxidized ferredoxin <=> 3-Methylbutanoyl-CoA + CO2 + 2 Reduced ferredoxin + H+
Equation
C00233 + C00010 + 2 C00139 <=> C02939 + C00011 + 2 C00138 + C00080
Reaction class
RC00004  C00010_C02939
RC02833  C00233_C02939
Enzyme
1.2.7.7
Pathway
rn00280  Valine, leucine and isoleucine degradation
rn01100  Metabolic pathways
rn01210  2-Oxocarboxylic acid metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.7  With an iron-sulfur protein as acceptor
    1.2.7.7
     R08566  4-Methyl-2-oxopentanoate + CoA + 2 Oxidized ferredoxin <=> 3-Methylbutanoyl-CoA + CO2 + 2 Reduced ferredoxin + H+
Orthology
K00186  2-oxoisovalerate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.7]
K00187  2-oxoisovalerate ferredoxin oxidoreductase beta subunit [EC:1.2.7.7]
K00188  2-oxoisovalerate ferredoxin oxidoreductase delta subunit [EC:1.2.7.7]
K00189  2-oxoisovalerate/pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.7 1.2.7.1]
LinkDB

KEGG   RCLASS: RC02833
Entry
RC02833                     RClass                                 
Definition
C5a-C5a:C6a+*-*+S2a:C1b+O5a-C1b+O5a
Reactant pair
C00026_C00091    C00026_C16254    C00100_C00109
C00233_C02939    C00233_C15975    C00322_C00527
C00322_C06157
Related class
Reaction
R01197 R01199 R01700 R01702 R01933 R01940 R06987 R08549
R08566
Enzyme
1.2.1.105       1.2.1.-         1.2.4.2         1.2.4.4         
1.2.4.-         1.2.7.1         1.2.7.3         1.2.7.7         
1.2.7.11        2.3.1.54
Pathway
rn00020  Citrate cycle (TCA cycle)
rn00280  Valine, leucine and isoleucine degradation
rn00380  Tryptophan metabolism
rn00640  Propanoate metabolism
rn00720  Other carbon fixation pathways
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
rn01210  2-Oxocarboxylic acid metabolism
RModule
RM044  2-Oxocarboxylic acid conversion to its CoA derivative
RM903  Oxidative decarboxylation of 2-oxoacid to form its CoA derivative
Orthology
K00164  2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
K00167  2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4]
K00169  pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
K00170  pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
K00171  pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
K00172  pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
K00174  2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
K00175  2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
K00176  2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]
K00177  2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]
K00186  2-oxoisovalerate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.7]
K00187  2-oxoisovalerate ferredoxin oxidoreductase beta subunit [EC:1.2.7.7]
K00188  2-oxoisovalerate ferredoxin oxidoreductase delta subunit [EC:1.2.7.7]
K00189  2-oxoisovalerate/pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.7 1.2.7.1]
K00382  dihydrolipoyl dehydrogenase [EC:1.8.1.4]
K00656  formate C-acetyltransferase [EC:2.3.1.54]
K00658  2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
K01616  multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
K11381  2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]
K15791  2-oxoadipate dehydrogenase E1 component [EC:1.2.4.-]

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