KEGG   REACTION: R08567
Entry
R08567                      Reaction                               
Name
(S)-3-methyl-2-oxopentanoate:ferredoxin oxidoreductase (decarboxylating; CoA-2-methylbutanoylating)
Definition
(S)-3-Methyl-2-oxopentanoic acid + CoA + 2 Oxidized ferredoxin <=> (S)-2-Methylbutanoyl-CoA + CO2 + 2 Reduced ferredoxin + H+
Equation
C00671 + C00010 + 2 C00139 <=> C15980 + C00011 + 2 C00138 + C00080
Reaction class
RC00004  C00010_C15980
RC02856  C00671_C15980
Enzyme
1.2.7.7
Pathway
rn00280  Valine, leucine and isoleucine degradation
rn01100  Metabolic pathways
rn01210  2-Oxocarboxylic acid metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.7  With an iron-sulfur protein as acceptor
    1.2.7.7
     R08567  (S)-3-Methyl-2-oxopentanoic acid + CoA + 2 Oxidized ferredoxin <=> (S)-2-Methylbutanoyl-CoA + CO2 + 2 Reduced ferredoxin + H+
Orthology
K00186  2-oxoisovalerate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.7]
K00187  2-oxoisovalerate ferredoxin oxidoreductase beta subunit [EC:1.2.7.7]
K00188  2-oxoisovalerate ferredoxin oxidoreductase delta subunit [EC:1.2.7.7]
K00189  2-oxoisovalerate/pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.7 1.2.7.1]
LinkDB

KEGG   RCLASS: RC02856
Entry
RC02856                     RClass                                 
Definition
C5a-C5a:C6a+*-*+S2a:C1c+O5a-C1c+O5a
Reactant pair
C00141_C00630    C00141_C15977    C00671_C15979
C00671_C15980
Related class
Reaction
R01701 R04225 R07160 R08567
Enzyme
1.2.4.4         1.2.7.7
Pathway
rn00280  Valine, leucine and isoleucine degradation
rn01100  Metabolic pathways
rn01210  2-Oxocarboxylic acid metabolism
RModule
RM044  2-Oxocarboxylic acid conversion to its CoA derivative
RM903  Oxidative decarboxylation of 2-oxoacid to form its CoA derivative
Orthology
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
K00167  2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4]
K00186  2-oxoisovalerate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.7]
K00187  2-oxoisovalerate ferredoxin oxidoreductase beta subunit [EC:1.2.7.7]
K00188  2-oxoisovalerate ferredoxin oxidoreductase delta subunit [EC:1.2.7.7]
K00189  2-oxoisovalerate/pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.7 1.2.7.1]
K11381  2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]

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