KEGG   REACTION: R09262
Entry
R09262                      Reaction                               
Definition
7,9,12-Octaketide intermediate 1 + NADPH + H+ <=> 7,9,12-Octaketide intermediate 2 + NADP+
Equation
Comment
ketoreductase, ActIII
Reaction class
RC00001  C00005_C00006
RC00144  C18327_C18328
Enzyme
1.1.1.-
Pathway
rn01056  Biosynthesis of type II polyketide backbone
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Orthology
K12420  ketoreductase [EC:1.1.1.-]
LinkDB

KEGG   RCLASS: RC00144
Entry
RC00144                     RClass                                 
Definition
C1y-C5x:*-*:C1x+C1x+O1a-C1x+C1x+O5x
Reactant pair
Related class
Reaction
Enzyme
1.1.1.50        1.1.1.51        1.1.1.52        1.1.1.53        
1.1.1.145       1.1.1.147       1.1.1.152       1.1.1.163       
1.1.1.206       1.1.1.209       1.1.1.210       1.1.1.213       
1.1.1.226       1.1.1.236       1.1.1.245       1.1.1.270       
1.1.1.277       1.1.1.278       1.1.1.357       1.1.1.391       
1.1.1.392       1.1.1.393       1.1.1.-         1.1.99.26       
1.14.14.69      1.14.19.79      1.14.-.-
Pathway
rn00100  Steroid biosynthesis
rn00120  Primary bile acid biosynthesis
rn00140  Steroid hormone biosynthesis
rn00905  Brassinosteroid biosynthesis
rn00906  Carotenoid biosynthesis
rn00930  Caprolactam degradation
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn00981  Insect hormone biosynthesis
rn00984  Steroid degradation
rn01056  Biosynthesis of type II polyketide backbone
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
RModule
RM017  Ring cleavage via Baeyer-Villiger oxidation
Orthology
K00037  3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225]
K00089  3alpha-hydroxysteroid 3-dehydrogenase [EC:1.1.1.213 1.1.1.357]
K04119  aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K05296  3(or 17)beta-hydroxysteroid dehydrogenase [EC:1.1.1.51]
K05354  tropinone reductase II [EC:1.1.1.236]
K08081  tropinone reductase I [EC:1.1.1.206]
K09588  3beta,22alpha-dihydroxysteroid 3-dehydrogenase [EC:1.14.19.79]
K09589  steroid 3-oxidase [EC:1.14.-.-]
K09827  3-keto steroid reductase [EC:1.1.1.270]
K12420  ketoreductase [EC:1.1.1.-]
K13373  17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
K17754  cyclopentanol dehydrogenase [EC:1.1.1.163]
K19960  cyclohexanol dehydrogenase [EC:1.1.1.245]

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