KEGG   REACTION: R09472
Entry
R09472                      Reaction                               
Name
4-(6-hydroxypyridin-3-yl)-4-oxobutanoate,NADH:oxygen oxidoreductase (3-hydroxylating, succinate semialdehyde releasing)
Definition
6-Hydroxy-3-succinoylpyridine + 2 NADH + 2 H+ + Oxygen <=> 2,5-Dihydroxypyridine + Succinate semialdehyde + 2 NAD+ + H2O
Equation
Reaction class
RC00001  C00003_C00004
RC03005  C01059_C19631
RC03006  C00232_C19631
Enzyme
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00811  Nicotine degradation, pyrrolidine pathway, nicotine => succinate semialdehyde
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.163
     R09472  6-Hydroxy-3-succinoylpyridine + 2 NADH + 2 H+ + Oxygen <=> 2,5-Dihydroxypyridine + Succinate semialdehyde + 2 NAD+ + H2O
Orthology
K15359  6-hydroxy-3-succinoylpyridine 3-monooxygenase [EC:1.14.13.163]
K18276  6-hydroxy-3-succinoylpyridine 3-monooxygenase [EC:1.14.13.163]
Other DBs
RHEA: 33930
LinkDB

KEGG   RCLASS: RC03005
Entry
RC03005                     RClass                                 
Definition
C8y-C8y:C5a+*-*+O1a:C8x+C8x-C8x+C8x
Reactant pair
Related class
Reaction
Enzyme
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K15359  6-hydroxy-3-succinoylpyridine 3-monooxygenase [EC:1.14.13.163]
K18276  6-hydroxy-3-succinoylpyridine 3-monooxygenase [EC:1.14.13.163]

KEGG   RCLASS: RC03006
Entry
RC03006                     RClass                                 
Definition
C4a-C5a:*-C8y:C1b+O4a-C1b+O5a
Reactant pair
Related class
Reaction
Enzyme
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K15359  6-hydroxy-3-succinoylpyridine 3-monooxygenase [EC:1.14.13.163]
K18276  6-hydroxy-3-succinoylpyridine 3-monooxygenase [EC:1.14.13.163]

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